Amylasecsfccnc
A test that measures the level of amylase enzyme in the fluid surrounding the brain and spinal cord.
{"CSF amylase is a digestive enzyme that can indicate pancreatic or nervous system problems when found in spinal fluid","Elevated levels may suggest pancreatitis, meningitis, or brain injury","The test requires a lumbar puncture (spinal tap) to collect the sample","Results help doctors diagnose conditions affecting the pancreas or central nervous system","This is a specialized test not commonly performed as a routine screening"}
Key facts at a glance
- LOINC
- 14389-1
- Short code
- Amylase CSF-cCnc
- Synonyms
- Amylase CSF-cCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What is this test?
The Cerebrospinal Fluid (CSF) Amylase test measures the amount of amylase, a digestive enzyme normally produced by the pancreas and salivary glands, in the fluid that surrounds your brain and spinal cord. This test is not routine and is ordered by doctors only when they suspect specific medical conditions.
Why is it performed?
Doctors may order this test when they need to investigate: acute pancreatitis that might be affecting the nervous system, infections or inflammation of the membranes surrounding the brain (meningitis), brain injuries or tumors, or leakage of pancreatic enzymes into the cerebrospinal fluid. The test helps determine whether problems in the pancreas or nervous system are present.
How is the sample collected?
The sample is collected through a procedure called a lumbar puncture or spinal tap. During this procedure, a healthcare provider inserts a thin needle between the bones in your lower spine to withdraw a small amount of cerebrospinal fluid. The area will be numbed with local anesthetic to minimize discomfort. After the procedure, you may be asked to lie flat for a short time to reduce the risk of headache.
What do the results mean?
Results are reported as units per liter (U/L). Normal CSF amylase levels are typically low or undetectable. Elevated levels may indicate pancreatitis, meningitis, subarachnoid hemorrhage, brain tumors, or traumatic brain injury. Your doctor will interpret your results based on your symptoms, medical history, and other test findings.
Are there any risks?
The main risks of lumbar puncture include headache, back pain, bleeding, or infection at the puncture site. In rare cases, a brain herniation can occur if there is increased pressure in the skull. Your healthcare team will take precautions to minimize these risks.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to fast before this test?
How long does it take to get results?
Is the lumbar puncture painful?
What happens if my results are abnormal?
Sources
- 1
- 2
- 3ARUP Consult - AmylaseSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy