Skip to content

Amylaseigerast

Published: August 9, 2026Updated: August 16, 2026

This blood test checks whether your immune system has allergic antibodies (IgE) against amylase, an enzyme found in saliva, pancreatic secretions, and some baking products.

Quick summary

{"A simple blood test that detects allergic antibodies to amylase","Helps diagnose amylase allergy, which may cause reactions to certain foods or baker's asthma","No food restrictions needed before this test","Results are reported as positive or negative for amylase-specific IgE"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103009-7
Short code
Amylase IgE RAST
Synonyms
Amylase IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The Amylase IgE test is a blood test that looks for specific allergic antibodies called immunoglobulin E (IgE) in your blood. These antibodies are produced by your immune system when it reacts to amylase, a digestive enzyme found naturally in your saliva and pancreas, and also used in commercial baking.

How is the test done?

A healthcare professional will draw a small blood sample from a vein in your arm. The sample is then sent to a laboratory where it is tested using a method called Radioallergosorbent Test (RAST). This test can detect whether IgE antibodies specific to amylase are present in your blood.

Do I need to prepare for the test?

No special preparation is needed. You do not need to fast before this test. You can continue taking your regular medications unless your doctor instructs otherwise. Unlike skin prick tests, this blood test is not affected by antihistamines or other allergy medications.

What do the results mean?

Your results will typically be reported as either 'Positive' (indicating amylase-specific IgE antibodies were detected) or 'Negative' (no amylase-specific IgE antibodies detected). A positive result suggests you may have an allergy to amylase, but your doctor will interpret this in the context of your symptoms and medical history.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

What is amylase and where is it found?
Amylase is an enzyme that helps break down starches in food. It is naturally produced in your saliva and pancreas. Commercially, amylase is derived from fungal or bacterial sources and used in baking to help bread rise and in the production of certain foods and medications.
What symptoms would suggest an amylase allergy?
Symptoms may include skin reactions like hives or eczema, digestive problems such as nausea or stomach pain, respiratory issues like sneezing or asthma-like symptoms (especially in bakers), and in severe cases, anaphylaxis. Symptoms typically occur after exposure to amylase-containing foods or substances.
How is this different from a skin prick test?
Unlike skin prick tests, this blood test does not expose you to allergens directly and is not affected by medications like antihistamines. It can be performed safely even if you have severe allergic conditions or skin conditions that would make skin testing difficult.
What should I do if my test is positive?
If your test is positive, discuss the results with your doctor or an allergist. They may recommend avoiding amylase-containing products, reading food labels carefully, and possibly carrying emergency medication if you have a history of severe reactions. Your doctor will help create a management plan based on your specific situation.
Can the test results change over time?
Yes, allergy test results can change. Some people may outgrow allergies, while others may develop new ones. If your symptoms change or you continue to have allergic reactions despite negative results, your doctor may recommend repeat testing or additional evaluation.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy