Complete Blood Count (CBC): What This Common Blood Test Tells Your Doctor
A blood test that measures different forms of amylase enzyme to help diagnose pancreatic and salivary gland disorders.
{"Amylase isoenzymes test measures two main types: pancreatic (P-type) and salivary (S-type)","Elevated levels may indicate pancreatitis, pancreatic cancer, or salivary gland inflammation","The test helps determine the source of amylase elevation in the blood","Blood is drawn from a vein and sent to a laboratory for analysis","Results are interpreted by comparing the ratio of P-type to S-type amylase"}
Key facts at a glance
- LOINC
- 14589-6
- Short code
- Amylase Isos SerPl-Imp
- Synonyms
- Amylase Isos SerPl-Imp
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
A complete blood count, or CBC, is a routine blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. It gives your healthcare team a snapshot of your overall health and helps detect many conditions.
The amylase isoenzymes test measures different forms of the amylase enzyme in your blood. Amylase is a digestive enzyme that helps break down carbohydrates in your food. There are two main types (isoenzymes): pancreatic amylase (produced by the pancreas) and salivary amylase (produced by salivary glands). This test helps doctors determine which organ is producing excess amylase when levels are elevated.
The test is performed by drawing a small sample of blood, usually from a vein in your arm. A trained clinician cleans the site, wraps a band around your upper arm, and collects the sample into a tube. The procedure takes only a few minutes, and you can return to your normal activities right afterward.
A healthcare professional will draw a small blood sample from a vein in your arm. The blood is collected into a tube and sent to a laboratory for analysis. The lab will separate and measure the different types of amylase isoenzymes to determine the ratio between pancreatic and salivary types.
Your doctor may order this test as part of a routine checkup, to look into symptoms such as fatigue, weakness, fever, or unexplained bruising, or to monitor an existing condition such as anemia, infection, or a blood disorder, and to see how a treatment is affecting your blood cells.
Your doctor may order this test if you have symptoms of pancreatic or salivary gland problems, such as severe abdominal pain, nausea, vomiting, or swelling of the salivary glands. It helps distinguish between conditions affecting the pancreas versus the salivary glands.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated pancreatic amylase (P-type) typically indicates acute or chronic pancreatitis, pancreatic cancer, pancreatic duct obstruction, or pancreatic injury. Elevated salivary amylase (S-type) may occur with salivary gland inflammation or infection, dental problems, or use of certain medications. The ratio between P-type and S-type helps pinpoint the source of the problem. Very low levels may indicate pancreatic insufficiency or advanced chronic pancreatitis.
Frequently asked questions
Do I need to fast before this test?
What do abnormal results mean?
Is the test painful?
Sources
- 1
- 2
- 3ARUP Consult - AmylaseSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy