Amylases1serplccnc

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures the level of amylase, an enzyme primarily produced by the pancreas and salivary glands to help digest carbohydrates.

Quick summary

{"Amylase is an enzyme that breaks down starch and glycogen in your body","This test helps diagnose pancreatic disorders such as pancreatitis","Elevated levels may indicate pancreatic inflammation, blockage, or other conditions","The test is performed on a blood sample drawn from your arm","Results are typically available within a few days"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC: 1806-9
Short code: Amylase S1 SerPl-cCnc
Synonyms: Amylase S1 SerPl-cCnc
Category: chemistry
Sample: serum
Container: Red-top tube (SST)
Units: N/A
Critical range: — – 500 N/A
Fasting: false
Population: adult
Sex: all
Age range: 18–65 years
Specimen volume: 5 mL
Stability: Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max: 500
Lipemia max: 1000
Icterus max: 500
TAT: 4–24 hours
Order: routine

What is this test?

The serum amylase test measures the amount of amylase in your blood. Amylase is a digestive enzyme produced mainly by the pancreas (pancreatic amylase) and salivary glands (salivary amylase). Its primary function is to break down carbohydrates (starches) into simpler sugars that your body can absorb. When the pancreas or salivary glands are damaged or diseased, amylase levels in the blood can rise or fall, providing important diagnostic information.

How is the test performed?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The sample is then sent to a laboratory for analysis. You do not need to fast before this test, though your doctor may instruct you to do so based on your specific situation. The procedure only takes a few minutes and is generally well-tolerated.

What do the results mean?

Normal amylase levels typically range from 30 to 110 units per liter (U/L), though reference ranges may vary slightly between laboratories. Elevated amylase levels may indicate acute or chronic pancreatitis, pancreatic duct obstruction, pancreatic cancer, gallbladder disease, or kidney dysfunction. Low levels may be seen in chronic pancreatitis, pancreatic insufficiency, or liver disease. Your doctor will interpret your results in the context of your symptoms and other test findings.

Are there any risks?

The risks associated with this test are minimal and include slight pain or bruising at the injection site, lightheadedness, and in rare cases, infection. These side effects are usually temporary and resolve quickly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before the amylase test?

Fasting is typically not required for a serum amylase test. However, follow your healthcare provider's specific instructions, as they may recommend fasting based on your individual circumstances or if other tests are being performed simultaneously.

What can cause false elevations in amylase?

Several factors can cause temporarily elevated amylase levels without pancreatic disease, including: certain medications (such as birth control pills, steroids, diuretics), alcohol consumption, kidney disease, salivary gland infections or blockages, and gastrointestinal conditions like peptic ulcers or appendicitis. Always inform your doctor about all medications you are taking.

How is amylase different from lipase?

While both are pancreatic enzymes used to diagnose pancreatic disorders, they have different functions and patterns. Amylase breaks down carbohydrates, while lipase digests fats. In acute pancreatitis, amylase typically rises and returns to normal faster (within 3-5 days), while lipase remains elevated longer (up to 10-14 days). Often, both tests are ordered together for a more complete evaluation.

What happens if my amylase levels are abnormal?

An abnormal amylase result does not necessarily mean you have a serious condition. Your healthcare provider will consider your symptoms, medical history, and other test results to determine the cause. Additional tests such as lipase, imaging studies (ultrasound, CT scan), or repeat testing may be recommended to confirm a diagnosis.

Can amylase levels be too low?

Low amylase levels are less common but can occur in chronic pancreatitis, pancreatic cancer that has destroyed much of the pancreas, severe liver disease, or conditions causing pancreatic insufficiency. If your results are low, your doctor will investigate the underlying cause.

Sources

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy