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Amylasesalccnc

Published: August 9, 2026Updated: August 16, 2026

A test that measures the level of amylase enzyme in saliva to evaluate salivary gland function.

Quick summary

{"Measures amylase enzyme activity in saliva","Helps diagnose salivary gland disorders","Non-invasive test using saliva sample","Also reflects stress levels and autonomic function"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74992-9
Short code
Amylase Sal-cCnc
Synonyms
Amylase Sal-cCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The salivary amylase test measures the amount and activity of amylase enzyme in your saliva. Amylase is a digestive enzyme produced primarily by the salivary glands and pancreas that helps break down carbohydrates in food. This test evaluates how well your salivary glands are functioning.

Why is it performed?

This test is ordered to diagnose and monitor conditions affecting the salivary glands, such as infections, inflammation (sialadenitis), blockages (salivary stones), or autoimmune diseases like Sjögren's syndrome. It may also be used to assess salivary gland function before certain medical treatments.

How is the test done?

The test is simple and non-invasive. You will be asked to provide a saliva sample, usually by spitting into a sterile container or by placing a collection swab in your mouth. You may be asked to fast or avoid eating/drinking for a certain period before the sample collection. The sample is then sent to a laboratory for analysis.

What do the results mean?

Elevated salivary amylase levels may indicate salivary gland infection, inflammation, or obstruction. Low levels may suggest decreased salivary gland function, which can occur with certain autoimmune conditions or as a side effect of medications. Your healthcare provider will interpret your results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is there any preparation needed before the test?
You may be asked to fast (not eat or drink) for a certain period before the test, typically 1-2 hours. Avoid smoking, chewing gum, or brushing your teeth before the sample collection, as these can affect saliva production and composition.
Is the test painful?
No, the salivary amylase test is completely painless. It only requires you to provide a saliva sample through spitting or using a swab.
How long does it take to get results?
Results are typically available within 1-3 days, depending on the laboratory. Your healthcare provider will inform you when your results are ready.
What can affect my salivary amylase levels?
Several factors can influence salivary amylase levels, including: time of day (levels tend to be higher in the morning), recent food intake, stress levels, certain medications, smoking, and hydration status. It's important to follow any pre-test instructions provided by your healthcare provider.
Do I need to see a specialist for this test?
Your primary care doctor can order this test. However, depending on the results, you may be referred to a dentist, oral surgeon, or ENT (ear, nose, and throat) specialist for further evaluation and treatment.
  1. 1
    MedlinePlus - Salivary Gland TestsSource
  2. 2
    Mayo Clinic Laboratories - Amylase, SalivaSource
  3. 3
    ARUP Laboratories - Salivary AmylaseSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy