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Amylasescfrserpl

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures the level of amylase enzyme, which helps digest carbohydrates and is produced by the salivary glands and pancreas.

Quick summary

{"Amylase is an enzyme that breaks down carbohydrates in your food","This test measures both salivary and pancreatic amylase in your blood","It helps diagnose conditions affecting the pancreas, such as pancreatitis","Abnormal levels may indicate problems with salivary glands or pancreas","The test requires a simple blood draw"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25313-8
Short code
Amylase S CFr SerPl
Synonyms
Amylase S CFr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The serum amylase test measures the amount of amylase enzyme in your blood. Amylase is produced mainly by two sources: the salivary glands (salivary amylase) and the pancreas (pancreatic amylase). This test typically measures total amylase, which includes both types. The enzyme plays a crucial role in breaking down starches and carbohydrates in the food you eat.

Why do I need this test?

Your healthcare provider may order this test if you have symptoms suggesting a problem with your pancreas or salivary glands. These symptoms may include severe abdominal pain, nausea, vomiting, loss of appetite, or fever. The test helps doctors diagnose conditions like acute or chronic pancreatitis, pancreatic cancer, salivary gland infections, or other digestive disorders.

How is the test performed?

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The blood sample will be sent to a laboratory for analysis. The procedure only takes a few minutes and is generally well-tolerated. You may experience slight bruising or soreness at the needle site, but this usually resolves quickly.

What do the results mean?

Normal amylase levels vary slightly between laboratories. High levels of amylase in the blood may indicate acute pancreatitis, chronic pancreatitis, pancreatic cancer, gallstones, or salivary gland inflammation. Low levels may suggest pancreatic insufficiency or chronic pancreatic disease. Your doctor will interpret your results along with other tests and your overall health condition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
Fasting is typically not required for a serum amylase test. However, follow any specific instructions provided by your healthcare provider. Some medications may affect test results, so inform your doctor about all medications you are taking.
Are there any risks associated with this test?
The risks are minimal and similar to any standard blood draw. These may include slight pain or bruising at the injection site, dizziness, or in rare cases, infection. The procedure is generally safe and well-tolerated by most patients.
How long does it take to get results?
Results are usually available within 24-48 hours, depending on the laboratory. Your healthcare provider will contact you with the results or discuss them at your follow-up appointment.
What other tests might be done with amylase?
Your doctor may also order a lipase test (another pancreatic enzyme), complete metabolic panel, complete blood count (CBC), or imaging studies like ultrasound or CT scan to get a more complete picture of your condition.
Can amylase levels be high without pancreatitis?
Yes, elevated amylase levels can occur due to other conditions including salivary gland infections or inflammation, kidney disease, certain medications, gastrointestinal conditions like peptic ulcers or appendicitis, and in some cases, pancreatic cancer. Your doctor will consider these factors when interpreting your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy