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Complete Blood Count (CBC)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antinuclear antibodies in your blood or peritoneal fluid, which may help diagnose autoimmune conditions affecting the abdomen.

Quick summary

{"Measures antibodies that may attack your body's own cells","Helps diagnose autoimmune diseases like lupus and rheumatoid arthritis","Sample is typically collected from blood (serum)","Results help doctors understand if your immune system is overactive","Positive results require further testing to confirm diagnosis"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110887-7
Short code
ANA Msmt Prt
Synonyms
ANA Msmt Prt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test? A complete blood count, also called a CBC, is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. These cells carry oxygen, fight infection, and help your blood clot the way it should.

The Nuclear Antibody test, also known as ANA (Antinuclear Antibody), detects specific proteins called antibodies in your blood. Normally, your immune system makes antibodies to fight off harmful substances like viruses and bacteria. However, sometimes your immune system can mistakenly make antibodies that attack your own body's healthy cells—this is called an autoimmune response.

Why is it done? This test is often part of a routine checkup to assess your overall health. It can also help find the cause of symptoms such as fatigue, weakness, fever, or unusual bruising, diagnose conditions like anemia or infection, and monitor how a treatment or medication is working over time.

Your doctor may order this test if you have symptoms suggesting an autoimmune disorder, such as joint pain, fatigue, skin rashes, fever, or unexplained inflammation in the body. When the test is performed on peritoneal fluid (fluid from the abdominal cavity), it may help identify autoimmune conditions that specifically affect the peritoneum or abdominal lining.

How is the sample collected? A member of your care team will draw a small amount of blood, usually from a vein on the inside of your elbow or the back of your hand. The site is cleaned, a needle is inserted, and the blood is collected into a tube. The process takes only a few minutes, and a bandage is placed on the site afterward.

For this test, a healthcare professional will collect a blood sample from a vein in your arm. The blood is then sent to a laboratory where technicians look for antinuclear antibodies. In some cases, peritoneal fluid may also be tested if your doctor suspects abdominal involvement of an autoimmune condition.

Understanding your results. Your report will list a measured value for each blood cell type along with a reference range, which is the usual range seen in healthy people. Values that are higher or lower than this range can point to many different conditions, so it is important to review your results with your doctor, who can explain what they mean for your health.

A positive result means that antinuclear antibodies were found in your sample. However, a positive result does not always mean you have a disease. Some healthy people, especially older adults, may have low levels of these antibodies. Your doctor will interpret your results along with your symptoms and other test results to make an accurate diagnosis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The Nuclear Ab test is primarily used to screen for autoimmune diseases such as Systemic Lupus Erythematosus (SLE), rheumatoid arthritis, scleroderma, and polymyositis. When found in peritoneal fluid, it may indicate autoimmune peritonitis or peritoneal involvement in systemic autoimmune diseases. This test is often the first step in diagnosing these conditions, followed by more specific antibody tests to confirm the exact type of autoimmune disorder.

Frequently asked questions

Do I need to fast before this test?
No, you do not need to fast before the Nuclear Ab test. You can eat and drink normally unless your doctor instructs otherwise.
Will the test hurt?
You may feel a brief sting or pinch when the needle is inserted to draw your blood. This is usually well-tolerated and lasts only a moment.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your doctor's office will contact you when results are ready.
What does a positive result mean?
A positive result indicates the presence of antinuclear antibodies, but it does not confirm a specific diagnosis. Your doctor will need to evaluate your symptoms, medical history, and possibly order additional tests to determine if you have an autoimmune condition.
Can medications affect my test results?
Certain medications, such as some blood pressure drugs, antibiotics, and anti-seizure medications, may cause false-positive results. Always inform your doctor about all medications and supplements you are taking.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy