Complete Blood Count (CBC): What This Common Blood Test Measures and Why Your Doctor May Order It
This blood test checks for IgA antibodies that target neutrophils, which can help diagnose certain autoimmune conditions affecting blood vessels.
{"A simple blood test that detects IgA antibodies against neutrophils","Helps diagnose autoimmune vasculitis conditions","Results are reported as positive or negative (presence/absence)","Usually ordered when symptoms suggest blood vessel inflammation","May be used alongside other tests for complete diagnosis"}
Key facts at a glance
- LOINC
- 17354-2
- Short code
- NEUTCYTIGA
- Synonyms
- ANCA IgA Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST)
- Units
- N/A
- Critical range
- 0.5 N/A – —
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunofluorescence
- CPT
- 86255
- Specimen volume
- 1 mL
- Stability
- Stable for 7 days at 2-8°C; 30 days at -20°C
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
A complete blood count (CBC) is a routine blood test that measures the different cells circulating in your blood, including red blood cells, white blood cells, and platelets. Doctors order it to check your overall health and to help detect conditions such as anemia, infections, and blood disorders.
The Neutrophil Cytoplasmic IgA Antibody test is a blood test that detects the presence of IgA-type antibodies that target neutrophils (a type of white blood cell). These antibodies are called ANCAs (Anti-Neutrophil Cytoplasmic Antibodies). When detected, they can indicate certain autoimmune disorders where the immune system mistakenly attacks the body's own blood vessels.
The test is done with a simple blood draw. A healthcare provider cleans a small spot on your arm, usually inside the elbow, wraps a band around your upper arm, and inserts a thin needle into a vein to collect a small sample. The sample is then sent to a laboratory, and the entire procedure usually takes only a few minutes.
A healthcare provider will draw a small blood sample from a vein in your arm. The blood is then sent to a laboratory where it is analyzed to detect the presence or absence of IgA antibodies against neutrophils. You do not need to fast before this test, and it typically takes 1-3 days to receive results.
Your results show the levels of each type of blood cell. Values that are higher or lower than the normal range may point to conditions such as anemia, infection, inflammation, or clotting problems. Your doctor interprets the numbers together with your symptoms and medical history, so an abnormal result does not always mean you have a serious illness.
Results are typically reported as 'Positive' (antibodies detected) or 'Negative' (no antibodies detected). A positive result suggests the presence of an autoimmune condition, particularly vasculitis (inflammation of blood vessels). Your doctor will interpret these results along with your symptoms, physical examination, and other test results to make an accurate diagnosis.
A CBC is very safe. The most common effects are minor, such as brief pain or bruising at the needle site. Some people feel dizzy or lightheaded during or after the draw, and there is a very small risk of infection or bleeding. These problems are rare and usually go away quickly on their own.
This is a standard blood test with minimal risks. You may experience slight bruising, soreness, or bleeding at the puncture site. These side effects are usually mild and resolve quickly. Serious complications are rare.
Reference range
NegativeN/A
No fasting required. No special patient preparation needed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The presence of neutrophil cytoplasmic IgA antibodies is primarily associated with ANCA-associated vasculitides, including granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis. These are serious conditions that cause inflammation of small and medium blood vessels. Detection of these antibodies helps in diagnosing and monitoring these autoimmune diseases, though the test is often used in combination with other clinical findings and laboratory tests for a complete assessment.
Frequently asked questions
Why do I need this test?
Do I need to prepare for the test?
Can this test diagnose a specific disease?
What happens if my result is positive?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy