Blood Test: What It Is and Why Your Doctor Ordered It
This test measures the level of androstenedione, a hormone, in the amniotic fluid surrounding the baby during pregnancy.
{"Androstenedione is a hormone produced by the adrenal glands and ovaries","This test helps assess fetal adrenal gland function and development","Abnormal levels may indicate certain genetic or hormonal conditions","The test is performed through amniocentesis","Results help doctors monitor pregnancy and plan appropriate care"}
Key facts at a glance
- LOINC
- 93731-8
- Short code
- Androst Amn-sCnc
- Synonyms
- Androst Amn-sCnc
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
A blood test is a common laboratory procedure in which a small sample of your blood is collected and analyzed to evaluate your overall health, screen for diseases, and measure the levels of cells, chemicals, and other substances circulating in your body.
The Androstenedione test measures the concentration of androstenedione, a steroid hormone, in the amniotic fluid. Amniotic fluid surrounds and protects the developing baby (fetus) in the womb. This test is performed as part of prenatal diagnostic testing, typically through a procedure called amniocentesis, where a small sample of amniotic fluid is collected and sent to a laboratory for analysis.
Your doctor may order this test to help diagnose a medical condition, monitor an existing illness or how well a treatment is working, check the function of organs such as the liver, kidneys, or heart, and screen for risk factors before symptoms appear.
This test is primarily used to evaluate fetal adrenal gland function and development. The adrenal glands produce various hormones, including androstenedione, which is a precursor to other important hormones like testosterone and estrogen. By measuring androstenedione levels in amniotic fluid, healthcare providers can gain insights into how well the fetal endocrine system is developing.
During the test, a healthcare professional will clean your skin, wrap a band around your upper arm, and draw a small amount of blood from a vein, usually in your arm, using a thin needle. The sample is sent to a laboratory for analysis, and the procedure usually takes only a few minutes.
The test requires collecting a sample of amniotic fluid through amniocentesis. During this procedure, a thin needle is inserted through the mother's abdomen into the uterus under ultrasound guidance to extract a small amount of amniotic fluid. The procedure is generally safe but carries a small risk of miscarriage, so it is typically performed when medically necessary.
Your results are compared with normal reference ranges. Abnormal values may point to infection, anemia, or problems with organs such as the liver or kidneys, but many factors, including medications, diet, and hydration, can affect the numbers. Your doctor will explain what your specific results mean and whether any follow-up testing or treatment is needed.
Results are interpreted in the context of the pregnancy timeline and other clinical findings. Your healthcare provider will explain what the androstenedione levels mean for your specific situation. Further testing may be recommended if abnormal levels are detected to determine the underlying cause.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal androstenedione levels in amniotic fluid may indicate fetal adrenal insufficiency or hyperplasia, which affects the baby's hormone production. This test helps in diagnosing certain genetic conditions that affect steroid hormone synthesis. It may also be used to assess fetal well-being in high-risk pregnancies. The results assist healthcare providers in making informed decisions about pregnancy management and planning for any special care the baby may need after birth.
Frequently asked questions
Is this test safe for my baby?
When is this test typically performed?
Will I need to prepare anything before the test?
How long does it take to get results?
Sources
- 1
- 2ACOG - AmniocentesisSource
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy