Complete Blood Count (CBC) Test
A test that measures the level of androstenedione, a hormone produced by the adrenal glands and ovaries, to help diagnose hormonal imbalances.
{"Androstenedione is a hormone that helps produce testosterone and estrogen","This test helps diagnose conditions like PCOS, adrenal disorders, or hormone-related issues","A blood sample is taken from a vein in your arm","Results help doctors understand symptoms like irregular periods, excess hair growth, or acne"}
Key facts at a glance
- LOINC
- 53344-8
- Short code
- ANDRO
- Synonyms
- Androst DBS-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube; dried blood spot (DBS) collection card for DBS specimens
- Units
- N/A
- Ref low
- 0.6
- Ref high
- 3.1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Immunoassay
- CPT
- 82157
- SNOMED
- 166688002
- Specimen volume
- 1 mL serum; DBS requires appropriate volume per collection device specifications (typically 50-75 µL whole blood per spot)
- Stability
- Serum: Room temperature 8 hours; Refrigerated (2-8°C) 7 days; Frozen (-20°C or lower) up to 6 months. DBS specimens: Stable at room temperature for several days to weeks depending on humidity and storage conditions; long-term storage at -20°C or lower recommended.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–120 hours
- Order
- routine
A complete blood count, or CBC, is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets. These cells carry oxygen throughout your body, fight infection, and help your blood clot properly, so this test gives your healthcare provider a broad picture of your overall health.
The androstenedione test measures the amount of androstenedione in your blood. Androstenedione is a hormone (called an androgen) produced mainly by the adrenal glands (located above your kidneys) and, in women, by the ovaries. It serves as a building block for other important hormones like testosterone and estrogen.
Your provider may order this test as part of a routine checkup, or to look into symptoms such as fatigue, weakness, fever, easy bruising, or unexplained bleeding. It can also help find conditions like anemia, infection, or blood disorders, and it is often used to monitor a chronic condition or to see how a treatment, such as chemotherapy, is affecting your blood cells.
Your doctor may order this test if you have symptoms of hormonal imbalance, such as: irregular or absent menstrual periods, excessive hair growth (hirsutism), severe acne, difficulty becoming pregnant, or signs of puberty occurring too early (in children). It helps doctors determine if your adrenal glands or ovaries are producing too much or too little of this hormone.
This test is done with a simple blood draw. A healthcare professional will place a tight band around your upper arm, clean the skin on the inside of your elbow, and insert a small needle into a vein to collect a sample into a tube. The process usually takes only a few minutes, and you may feel a brief pinch. After the needle is removed, pressure and a small bandage are applied to the site.
A healthcare professional will draw a small amount of blood from a vein in your arm using a needle. The blood sample is then sent to a laboratory for analysis. The test typically requires no special preparation, but follow your doctor's instructions about whether you need to fast or stop certain medications before the test.
Your results show whether the number, size, and features of your blood cells fall within normal ranges. Values that are too high or too low may point to conditions such as anemia, infection, inflammation, or clotting problems, but abnormal results do not confirm a diagnosis on their own. Your healthcare provider will interpret the numbers along with your symptoms, medical history, and other test results to decide whether further evaluation or treatment is needed.
Normal androstenedione levels vary by age, sex, and laboratory reference ranges. High levels may indicate conditions such as polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia, adrenal tumors, or ovarian tumors. Low levels may be due to adrenal insufficiency or ovarian failure. Your doctor will interpret your results along with your symptoms and other test results.
Reference range
Reference ranges vary by age, sex, and assay methodology. Typical adult ranges: Males 0.6-3.1 ng/mL; Females (premenopausal) 0.4-3.4 ng/mL; Females (postmenopausal) 0.3-2.5 ng/mL. Pediatric and adolescent ranges differ significantly and should be interpreted using age-specific reference intervals.N/A
No special preparation required. However, samples should be collected at a consistent time of day, preferably in the morning, as adrenal androgen secretion follows a diurnal pattern. In females, the phase of the menstrual cycle should be noted as levels vary cyclically.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The androstenedione test is primarily used to evaluate androgen excess disorders in women, such as PCOS, and to assess adrenal gland function. It helps differentiate between adrenal and ovarian sources of hormone excess. In children, it can help diagnose early or delayed puberty. The test is often used in combination with other hormone tests (like testosterone, DHEA-S, and LH/FSH) to get a complete picture of hormonal status.
Frequently asked questions
Do I need to prepare for the androstenedione test?
Are there any risks from the blood test?
How long does it take to get results?
What happens if my androstenedione levels are abnormal?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy