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Complete Blood Count (CBC): What This Common Blood Test Measures and When Your Doctor Uses It

Published: August 9, 2026Updated: August 15, 2026

A blood test that measures the level of androstenedione, a hormone produced by the adrenal glands, ovaries, and testes.

Quick summary

{"Androstenedione is a hormone that serves as a building block for testosterone and estrogen","This test helps doctors evaluate adrenal gland function and detect hormone imbalances","Abnormal levels may indicate conditions like adrenal hyperplasia, PCOS, or adrenal tumors","The test is performed on a blood sample drawn from a vein in your arm","Results are typically available within a few days"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
97756-1
Short code
ANDRO
Synonyms
Androst Fld-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (serum separator tube acceptable)
Units
N/A
Ref low
0.3
Ref high
3.5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Chemiluminescent Immunoassay (CLIA)
CPT
82157
SNOMED
167898009
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What is a complete blood count (CBC), and what does this routine blood test actually measure inside my body?

The androstenedione test measures the amount of androstenedione in your blood or other body fluids. Androstenedione is an androgen (male hormone) produced mainly by the adrenal glands, with smaller amounts made by the ovaries in women and testes in men. It serves as a precursor (building block) for other important hormones like testosterone and estrogen.

Why might my doctor order a CBC, and what can it reveal about my symptoms, infections, anemia, or overall health?

Your doctor may order an androstenedione test if you have symptoms of a hormone imbalance. For women, this may include irregular periods, excessive hair growth (hirsutism), acne, or difficulty becoming pregnant. For men, it may help evaluate early or delayed puberty. The test is also used to check adrenal gland function and may help diagnose conditions affecting the adrenal glands.

How should I prepare for my CBC blood draw, and do I need to fast, drink water, or adjust my medications beforehand?

Follow your doctor's instructions carefully. You may need to fast (not eat or drink anything except water) for 8-12 hours before the test. Certain medications can affect test results, so inform your doctor about all medications, supplements, or herbal products you are taking. Your doctor may ask you to stop certain medications temporarily. It's best to have the test done in the morning, as hormone levels can vary throughout the day.

What happens during a CBC blood test, from the moment the needle is placed in my arm to the laboratory analysis?

A healthcare professional will draw a blood sample from a vein in your arm using a small needle. You may feel a brief pinch or sting. The blood will be collected in a tube and sent to a laboratory for analysis. The procedure typically takes only a few minutes. There is minimal risk involved, though you may experience slight bruising or bleeding at the needle site.

What do my CBC results mean, and how do reference ranges help explain whether my red cells, white cells, or platelets are high or low?

Normal androstenedione levels vary by age, sex, and laboratory reference ranges. High levels may indicate conditions such as congenital adrenal hyperplasia, polycystic ovary syndrome (PCOS), adrenal tumors, or ovarian tumors. Low levels may be due to adrenal insufficiency or other adrenal disorders. Your doctor will interpret your results based on your symptoms, medical history, and other test results.

Reference range

Adult Male: 0.6-3.1 ng/mL; Adult Female (Premenopausal): 0.7-3.5 ng/mL; Adult Female (Postmenopausal): 0.3-2.7 ng/mL. Reference ranges vary by laboratory and assay methodology.N/A

Specimen: serum

No fasting required. Specimen should be collected in the morning (7-10 AM) when possible, as diurnal variation affects androstenedione levels. For females, the phase of the menstrual cycle should be noted as levels peak at mid-cycle.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The androstenedione test is clinically significant for diagnosing and monitoring conditions related to androgen excess or deficiency. It aids in identifying adrenal disorders such as congenital adrenal hyperplasia (a genetic condition affecting adrenal hormone production) and adrenal tumors. In women, it helps evaluate causes of hirsutism, acne, androgenetic alopecia, and menstrual irregularities. The test is also useful in assessing pubertal disorders and in the evaluation of infertility. Additionally, androstenedione measurements may be used alongside other hormone tests (such as testosterone, DHEA-S, and cortisol) to provide a comprehensive assessment of endocrine function.

Frequently asked questions

Is the androstenedione test painful?
The test involves a simple blood draw. You may feel a brief pinch or stinging sensation when the needle is inserted, but the discomfort is usually minimal and short-lived. Most people find the procedure tolerable.
Are there any risks associated with this test?
The risks are minimal and include slight bruising, bleeding, or soreness at the puncture site. In rare cases, fainting or infection may occur. These risks are generally low when the test is performed by trained healthcare professionals.
How long does it take to get results?
Results are typically available within 2-5 business days, depending on the laboratory. Your doctor will contact you with the results or discuss them at your follow-up appointment.
Can I take my regular medications before the test?
Some medications can affect androstenedione levels, including birth control pills, corticosteroids, and certain supplements. Always inform your doctor about all medications and supplements you are taking. Your doctor will advise you on whether to continue or temporarily stop any medications before the test.
Do I need to fast before the androstenedione test?
Fasting requirements may vary by laboratory. Some tests require fasting for 8-12 hours, while others do not. Follow your doctor's specific instructions. You can usually drink water during the fasting period.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy