Skip to content

Androstmsmtserpl

Published: August 9, 2026Updated: August 16, 2026

A test that measures the level of androstenedione, a steroid hormone produced by the adrenal glands, ovaries, and testes, which serves as a precursor to both testosterone and estrogen.

Quick summary

{"Androstenedione is a hormone that helps produce sex hormones like testosterone and estrogen","This test helps doctors evaluate conditions affecting hormone balance, such as PCOS, adrenal disorders, or excessive hair growth","The test is performed on a blood sample taken from your arm","Results are interpreted along with other hormone tests for accurate diagnosis"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110768-9
Short code
ANDRO
Synonyms
Androst Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top serum tube or serum separator tube (SST)
Units
N/A
Ref low
0.4
Ref high
3.5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Immunoassay
CPT
82157
SNOMED
104693000
Specimen volume
1-2 mL of serum
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 6 months
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What is this test?

The androstenedione test measures the amount of androstenedione in your blood. Androstenedione is a steroid hormone produced primarily by the adrenal glands in both men and women. In women, it is also produced by the ovaries, and in men by the testes. This hormone acts as a building block (precursor) for making testosterone and estrogen, the primary male and female sex hormones.

Why do I need this test?

Your doctor may order an androstenedione test if you have symptoms of hormonal imbalance, such as: excessive hair growth (hirsutism) on the face, chest, or back; irregular menstrual periods; acne; deepening of the voice; or unexplained weight gain. It helps doctors diagnose conditions like polycystic ovary syndrome (PCOS), adrenal gland disorders (such as congenital adrenal hyperplasia or adrenal tumors), or tumors of the ovaries or testes.

How is the test done?

A healthcare professional will draw a small blood sample from a vein in your arm using a needle. The sample is then sent to a laboratory for analysis. You may need to fast (not eat or drink anything except water) for several hours before the test, and your doctor may ask you to stop taking certain medications that could affect the results. For women, the test is sometimes performed at a specific point in the menstrual cycle as hormone levels naturally fluctuate.

What do the results mean?

Normal androstenedione levels vary based on age, sex, and the laboratory that performs the test. Elevated levels may indicate conditions such as PCOS, adrenal hyperplasia, adrenal tumors, or ovarian tumors. Low levels may suggest adrenal insufficiency or other adrenal disorders. Your doctor will interpret your results along with other hormone tests (such as testosterone, DHEA-S, and estrogen) to make an accurate diagnosis.

Reference range

Adult Male: 0.4-2.8 ng/mL; Adult Female: 0.5-3.5 ng/mL (varies by cycle phase and laboratory); Pediatric ranges vary by Tanner stageN/A

Specimen: serum

No fasting required. For females, document menstrual cycle phase as levels vary during the cycle. Specimen should be collected in the morning (7-10 AM) when possible due to diurnal variation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is there any preparation needed before the test?
You may need to fast for 8-12 hours before the test. Tell your doctor about all medications, supplements, or herbal products you are taking, as some can affect hormone levels. For women, the test timing may be important as hormone levels change throughout the menstrual cycle.
Are there any risks from the blood draw?
The risks are minimal and include slight pain, bruising, or bleeding at the puncture site. Some people may feel dizzy or faint during or after the blood draw. These symptoms usually resolve quickly.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your doctor's office will contact you with the results or discuss them at your follow-up appointment.
What happens if my androstenedione levels are abnormal?
Abnormal results alone do not provide a definitive diagnosis. Your doctor will consider your symptoms, medical history, and results from other tests (such as testosterone, DHEA-S, LH, FSH, and imaging studies if needed) to determine the cause and appropriate treatment plan.
Can lifestyle changes affect androstenedione levels?
While lifestyle changes alone may not significantly normalize abnormal androstenedione levels, maintaining a healthy weight, regular exercise, and balanced nutrition can help manage symptoms associated with hormonal imbalances, such as those seen in PCOS. Always follow your doctor's advice regarding treatment.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy