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Complete Blood Count (CBC): What This Blood Test Measures and When Your Doctor May Order It

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures androstenedione levels to evaluate hormone imbalances and adrenal or ovarian function.

Quick summary

{"Androstenedione is a hormone produced by the adrenal glands and ovaries","This test helps diagnose conditions like PCOS, adrenal disorders, and certain tumors","Blood is drawn from a vein, typically in the morning when hormone levels are highest","Results are compared to normal ranges that vary by sex and age","Abnormal levels may require further testing for proper diagnosis"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1853-1
Short code
ANDROSEM
Synonyms
Androst Smn-mCnc
Category
chemistry
Sample
serum
Container
Sterile specimen container
Units
N/A
Ref low
0.6
Ref high
3.1
Fasting
false
Population
adult
Sex
male
Age range
18–99 years
Method
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) or Immunoassay
CPT
82157
SNOMED
102731000
Specimen volume
1-2 mL
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 24 hours; Frozen (-20°C or below): 30 days for long-term storage
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

A complete blood count (CBC) is one of the most common blood tests. It measures the different cells that make up your blood, including red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. These measurements give your health care team a broad picture of your overall health and can help detect conditions such as anemia, infections, and certain blood disorders, often before symptoms appear.

The androstenedione test measures the amount of androstenedione in your blood. Androstenedione is a steroid hormone produced primarily by the adrenal glands in both men and women, and by the ovaries in women. It serves as a precursor to other hormones, including testosterone and estrogen. This test helps healthcare providers assess how well your endocrine system is functioning and can aid in diagnosing various hormonal disorders.

Your doctor may order a CBC as part of a routine checkup, before surgery, or to help evaluate symptoms such as fatigue, weakness, fever, frequent bruising, or unexplained bleeding. It is also used to monitor an ongoing condition, such as kidney disease, or to check how treatments like chemotherapy or certain long-term medications are affecting your blood cells over time.

Your doctor may order an androstenedione test if you are experiencing symptoms of hormone imbalance. In women, this may include irregular periods, excessive hair growth (hirsutism), acne, or signs of polycystic ovary syndrome (PCOS). In men, it may help evaluate early or delayed puberty. The test can also help detect adrenal gland disorders, such as congenital adrenal hyperplasia, adrenal tumors, or ovarian tumors that produce excess hormones.

Preparation for a CBC is usually very simple. You can normally eat and drink as usual unless your provider asks you to fast because other blood tests are being done at the same time. Tell your care team about all medicines, vitamins, and supplements you take, since some can influence your results. Being well hydrated before your appointment can also make your veins easier to find.

Your healthcare provider may ask you to fast for 8-12 hours before the blood draw. Certain medications, including birth control pills, corticosteroids, and hormone supplements, can affect test results. Inform your doctor about all medications and supplements you are taking. The test is typically performed in the morning, as hormone levels naturally fluctuate throughout the day and are usually highest in the morning hours.

During the test, a nurse or phlebotomist will clean a small area of skin on your arm, usually the inside of the elbow, with an antiseptic and wrap a band around your upper arm. A thin needle is inserted into a vein and a small sample of blood is collected into a tube. You may feel a brief sting or pinch, but the draw typically takes only a few minutes, and a small bandage is placed on the site afterward.

A healthcare professional will clean the injection site with alcohol and insert a needle into a vein, usually in your arm. You may feel a brief pinch or sting. The blood will be collected into a vial, and the needle will be removed. The process typically takes less than five minutes. After the test, you may have minor bruising or soreness at the injection site, which usually resolves quickly.

Your report will show each result alongside a normal reference range, often given in cells per microliter (µL). Values that are higher or lower than the range can suggest conditions such as anemia, infection, inflammation, or clotting problems, but a single abnormal number does not always mean you are sick. Your provider will interpret your results together with your symptoms, history, and other tests, so ask what they mean for you and whether follow-up is needed.

Normal androstenedione levels vary based on age, sex, and the laboratory that performs the test. Generally, adult female levels range from 0.7 to 2.6 ng/mL, while adult male levels range from 0.6 to 2.0 ng/mL. Your results will be interpreted in the context of your symptoms, medical history, and other test results. Abnormal levels do not necessarily indicate a serious condition but warrant further investigation by your healthcare provider.

Reference range

Reference ranges vary by assay method and laboratory. Generally, adult male reference range is approximately 0.6-3.1 ng/mL. Consult laboratory-specific reference values.N/A

Specimen: serum

No special preparation required. Specimen collection should be performed by trained personnel following standard clinical laboratory procedures.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated androstenedione levels in women may indicate polycystic ovary syndrome (PCOS), adrenal hyperplasia, ovarian tumors, or adrenal tumors. Symptoms may include hirsutism (excessive hair growth), acne, male-pattern baldness, and irregular menstrual cycles. In men, elevated levels are less common but may indicate testicular or adrenal tumors. Low levels may suggest adrenal insufficiency or hypogonadism. This test is often used alongside other hormone tests (such as testosterone, DHEA-S, and estrogen) to provide a complete picture of hormonal status.

Frequently asked questions

Does the test require fasting?
Your doctor may recommend fasting for 8-12 hours before the test. Follow the specific instructions provided by your healthcare provider.
Are there any risks associated with this test?
The risks are minimal and include minor bruising, bleeding, infection, or dizziness. These side effects are rare and usually resolve quickly.
How long does it take to get results?
Results are typically available within a few days to a week, depending on the laboratory. Your healthcare provider will contact you with the results.
Can medications affect my test results?
Yes, certain medications such as birth control pills, hormone therapy, corticosteroids, and some supplements can affect androstenedione levels. Always inform your doctor about all medications you are taking.
What happens if my results are abnormal?
Abnormal results do not always mean you have a serious condition. Your doctor will interpret the results in the context of your symptoms and may order additional tests to determine the cause of the imbalance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy