Antibody to *Aspergillus* (Serum) – IgG
This test measures the level of antibodies your immune system produces in response to exposure to *Aspergillus* fungi, commonly found in mold.
["Helps diagnose fungal infections caused by *Aspergillus* spores in the lungs or bloodstream."]
Key facts at a glance
- LOINC
- 47426-2
- Short code
- ASPNH
- Synonyms
- A nidulans H Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube without anticoagulant
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme Immunoassay (EIA) or Immunodiffusion for detection of Aspergillus nidulans H (hyphal) antibodies
- CPT
- 86606
- SNOMED
- 395130008
- Specimen volume
- 1-2 mL serum
- Stability
- Stable at room temperature for 8 hours; refrigerated (2-8°C) for 7 days; frozen (-20°C or below) for up to 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–168 hours
- Order
- routine
What This Test Measures
The test detects IgG antibodies specific to *Aspergillus* antigens, indicating past or ongoing exposure. IgG antibodies are part of your body’s long-term immune response and can remain detectable for months or years after exposure.
Why It’s Ordered
Your healthcare provider may order this test if you have symptoms like persistent cough, wheezing, or lung infections, or if you’ve had exposure to moldy environments. It’s also used in people with weakened immune systems (e.g., from HIV, chemotherapy, or organ transplants) who are at higher risk for serious fungal infections.
How the Test Works
A blood sample is taken, and the serum is analyzed to measure IgG antibody levels using an immunoassay method. This identifies whether your immune system has recognized and responded to *Aspergillus* antigens.
What the Results Mean
Positive results suggest past or current exposure to *Aspergillus*, but they don’t always confirm an active infection. False positives can occur, especially in people with long-term mold exposure or autoimmune conditions.
Reference range
Negative (antibodies not detected); Positive indicates presence of IgG antibodies against Aspergillus nidulans hyphal antigenN/A
No special preparation required. Specimen should be collected prior to initiation of antifungal therapy when possible, as treatment may affect antibody titers.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgG anti-Aspergillus
Frequently asked questions
Why might my doctor ask for this test?
What does a high or low result mean?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy