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: Aspergillus niger Antibody, Serum

Published: August 9, 2026Updated: August 15, 2026

: This test looks for antibodies your immune system makes against Aspergillus niger, a common environmental mold. It can help assess whether you have been exposed to or are reacting to this mold.

Quick summary

[": A positive result indicates immune exposure to Aspergillus niger but must be interpreted alongside your symptoms and other findings."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
31232-2
Short code
ASPNAB
Synonyms
A niger Ab Fld Ql
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top clot tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA) or Immunofluorescence Assay (IFA) for detection of Aspergillus niger-specific IgG/IgM antibodies
CPT
86606
SNOMED
3952009
Specimen volume
1-2 mL serum
Stability
Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
200
Icterus max
40
TAT
24–72 hours
Order
routine

: What This Test Measures

: The test detects antibodies (immune proteins) directed against Aspergillus niger, a mold found widely in soil, dust, and decaying plant material. The presence and level of these antibodies can show whether your body has recognized and responded to this mold.

: Why It May Be Ordered

: Your healthcare provider may order this test when evaluating respiratory or allergic-type symptoms that could relate to mold exposure. It is often used as part of a broader allergy or hypersensitivity workup rather than on its own.

: How the Sample Is Collected

: A blood sample is drawn from a vein in your arm and sent to the laboratory for analysis. No special preparation is usually required, though you should follow any instructions given by your provider.

: What Results Can Mean

: Results are typically reported in a qualitative or semi-quantitative form depending on the laboratory. A positive or elevated result suggests prior exposure or an immune response to the mold, but it does not by itself confirm disease. Your provider will interpret it together with your history, symptoms, and other tests.

Reference range

Negative: No detectable Aspergillus niger antibodies. Positive: Presence of Aspergillus niger-specific antibodies indicating exposure or infection. Results interpreted as Negative, Equivocal, or Positive based on assay-specific index/cutoff values.N/A

Specimen: serum

No fasting required. Patients on antifungal therapy (amphotericin B, voriconazole, itraconazole, posaconazole) should be noted as therapy may affect antibody response. Recent blood transfusions or immunoglobulin therapy may influence results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: Aspergillus niger Ab

Frequently asked questions

: Does a positive result mean I have a mold infection?
: Not necessarily. A positive result usually indicates exposure or an immune response to the mold rather than an active infection. Your provider will consider your symptoms and other test results to determine what it means for you.
: Is this the same as allergy testing?
: It is related but not identical. This test detects antibodies against Aspergillus niger and may be used as part of an allergy or hypersensitivity evaluation, but it is not a standard skin-prick allergy test and should be interpreted by your provider.
: Do I need to prepare for this test?
: In most cases no special preparation is needed. Follow any specific instructions from your healthcare provider or the laboratory performing the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy