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Antigen Antibody Screening Test for Infectious Agent (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that may indicate past or current exposure to certain infectious agents. It helps identify conditions like infections, immune responses, or previous vaccinations.

Quick summary

["This screening helps determine if you’ve been exposed to or have immunity against specific pathogens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22086-3
Short code
ASPNAB
Synonyms
A niger Ab Ser Ql
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA) or Immunofluorescence Assay (IFA) for detection of Aspergillus niger-specific IgG antibodies
CPT
86606
SNOMED
122793009
Specimen volume
1-2 mL of serum
Stability
Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What This Test Measures

The test detects specific antibodies (proteins produced by your immune system) that target particular infectious agents. These antibodies can appear after exposure to a virus, bacteria, or other pathogens, or after vaccination. The method used may involve immunoassay techniques to identify these antibodies in your serum or plasma sample.

Why It’s Ordered

Doctors may order this test to diagnose infections, evaluate immune responses, assess vaccination status, or screen for conditions like HIV, hepatitis, or other viral/bacterial exposures. It can also be used in research or pre-transfusion screening to check for infectious diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum (liquid part after clotting) or plasma (liquid part before clotting). This sample is then tested in a lab using specialized equipment to detect the presence of antibodies.

Common Uses and Clinical Contexts

This test is commonly used in routine health checks, pre-surgery evaluations, travel-related screening, or when monitoring chronic conditions. It can also be part of diagnostic workups for unexplained symptoms like fever, fatigue, or unexplained infections.

Reference range

Negative: No detectable Aspergillus niger antibodies; Positive: Presence of Aspergillus niger IgG antibodies detected, suggesting prior exposure or current infection. Titers and clinical correlation required for interpretation.N/A

Specimen: serum

No special preparation required. Fasting is not necessary for antibody detection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Infectious Disease Screen (Serum/Plasma)

Frequently asked questions

How long will it take to get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you once they are ready. If you have concerns, ask your doctor about expected timelines.
What does a positive result mean?
A positive result indicates the presence of antibodies against the tested infectious agent, suggesting past exposure, infection, or vaccination. However, it doesn’t always confirm the current state of your health—some infections may resolve without antibodies remaining detectable. Always discuss results with your doctor.
Can I fast before this test?
No fasting is required for this test. Blood is drawn at any time of day, and it does not affect the accuracy of antibody detection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy