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Serum or Plasma Bile Acids (Total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bile acids present in your blood, which are important for digestion and metabolism.

Quick summary

["Bile acids help break down fats and play a role in liver function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47427-0
Short code
ASPNB
Synonyms
A niger B Ab Ser Ql
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (EIA/ELISA)
CPT
86003
SNOMED
395140008
Specimen volume
1-2 mL serum
Stability
Stable for 7 days at 2-8°C; stable for 30 days at -20°C
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What Is Bile Acid Testing For?

Bile acids can be checked to evaluate liver function, bile flow, and conditions like bile duct blockages or liver disease. High levels may suggest liver issues or problems with bile production, while low levels could indicate malabsorption or other gastrointestinal concerns.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is then processed to separate serum or plasma for analysis. The test measures the concentration of bile acids using a specialized laboratory method.

What Might Affect Results?

Several factors could influence bile acid levels, including diet (e.g., high-fat meals), certain medications (like bile acid sequestrants), liver disease, gallbladder issues, or metabolic disorders. Recent meals or fasting status may also impact results.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions such as primary biliary cholangitis, biliary atresia, liver cirrhosis, or bile duct obstructions. It may also help assess patients with unexplained jaundice or gastrointestinal symptoms.

Reference range

NegativeN/A

Specimen: serum

No fasting required. Patient should be informed about the test purpose and procedure prior to blood draw.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Bile Acids

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like abdominal pain, jaundice (yellowing of skin/eyes), fatigue, or if they suspect liver or bile duct problems. Elevated levels may indicate bile flow issues, while abnormal results could prompt further investigation into liver function or metabolic disorders.
What do my results mean?
Results are typically compared to a reference range provided by your lab. While exact ranges vary by lab, abnormal levels (either high or low) may signal underlying health concerns that need evaluation by a healthcare provider.
How soon will I get results?
Results are usually available within 1–3 business days, depending on lab processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy