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: Aspergillus niger Specific IgE Antibody, Serum

Published: August 9, 2026Updated: August 16, 2026

: This blood test measures immunoglobulin E (IgE) antibodies directed against the mold Aspergillus niger. It helps determine whether a person has become sensitized to this mold, which can contribute to allergy symptoms or respiratory conditions.

Quick summary

[": A positive result indicates allergic sensitization to Aspergillus niger, but it must be interpreted alongside your symptoms and history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44031-3
Short code
ASPNIGB
Synonyms
A niger B Ab Ser Ql ID
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top clot activator tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-diffusion
CPT
86001
SNOMED
39512008
Specimen volume
1-2 mL serum (minimum 0.5 mL)
Stability
Serum stable at 2-8°C for 7 days; frozen at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles. Ship on cold packs if not frozen.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
48–168 hours
Order
routine

: What This Test Measures

: The test detects and measures the amount of allergen-specific IgE antibody your immune system produces against proteins from Aspergillus niger, a common environmental mold. IgE is the antibody class most closely linked to immediate allergic reactions. When your body has been exposed and sensitized to this mold, specific IgE antibodies appear in the blood and can be measured.

: Why Your Provider May Order It

: This test is typically ordered when a mold allergy or mold-related respiratory problem is suspected. Your provider may recommend it if you have persistent nasal congestion, sneezing, itchy or watery eyes, wheezing, coughing, or asthma-like symptoms that could be triggered by mold exposure, or if other allergy testing is being evaluated.

: How the Sample Is Collected

: A small blood sample is drawn from a vein, usually in your arm, at a clinic or laboratory. No special preparation such as fasting is generally required, though you should follow any specific instructions your ordering provider gives you. The serum is then separated and analyzed.

: What Results Can Mean

: Results are usually reported as a level or class of specific IgE. A detectable or elevated result suggests sensitization to Aspergillus niger, while an undetectable result makes allergy to this mold less likely. Sensitization does not always mean you will have symptoms, so results are interpreted together with your clinical history and other findings.

Reference range

Negative: No precipitating antibodies detected against Aspergillus niger B antigen. Positive: Precipitin lines detected indicating IgG/IgM antibodies against Aspergillus niger B antigen.N/A

Specimen: serum

No special preparation required. Patient does not need to fast prior to specimen collection. Recent antifungal therapy may affect antibody titers and should be noted on the requisition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Aspergillus niger is a widespread mold found in soil, decaying plant matter, and damp indoor environments. Specific IgE testing helps identify allergic sensitization to this mold and can support the evaluation of allergic rhinitis or mold-associated asthma. However, a positive result alone does not confirm a diagnosis of mold allergy or disease; clinicians combine it with symptom patterns, exposure history, physical examination, and sometimes other tests. Results should be reviewed by your healthcare provider in the context of your overall health.

Short name

: Aspergillus niger IgE

Frequently asked questions

: Do I need to fast before this test?
: Fasting is generally not required for allergen-specific IgE blood tests. Follow any instructions given by your healthcare provider or the laboratory performing the collection.
: Does a positive result mean I definitely have a mold allergy?
: No. A positive result shows that your immune system has been sensitized to Aspergillus niger, but it does not by itself prove that the mold is causing your symptoms. Your provider will interpret the result along with your symptoms, exposure history, and other test findings.
: Can I reduce mold exposure at home?
: Yes. Reducing indoor dampness, fixing leaks, improving ventilation, and cleaning visible mold can help lower exposure. Discuss any persistent symptoms with your healthcare provider so your situation can be properly evaluated.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy