Angiotensinogen (Serum)
This test measures the level of angiotensinogen, a protein in your blood that helps regulate blood pressure and fluid balance. It may be checked if you have suspected hereditary angioedema or other conditions affecting blood vessel function.
["Angiotensinogen levels help diagnose or monitor conditions linked to fluid and pressure regulation."]
Key facts at a glance
- LOINC
- 47428-8
- Short code
- ASPNHAB
- Synonyms
- A niger H Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) - red top or gold top tube
- Units
- N/A
- Ref low
- 0.35
- Ref high
- 0.69
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- Immunoassay (ImmunoCAP FEIA - Fluorescence Enzyme Immunoassay)
- CPT
- 86003
- SNOMED
- 39512009
- Specimen volume
- 0.5-1.0 mL serum (minimum 0.3 mL)
- Stability
- Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 12 months. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have symptoms like swelling in your face, throat, or digestive tract, or if you have a family history of hereditary angioedema—a rare condition causing sudden, severe swelling. It may also be used to monitor treatment for conditions affecting blood vessels or fluid balance.
What to Expect Before the Test
No special preparation is needed. You may have a blood draw from a vein in your arm, similar to other blood tests. If you’re on blood thinners, let your provider know before the test.
What the Results Mean
Results can help determine if you have abnormal protein levels linked to swelling or fluid issues. Your provider will interpret the results in the context of your symptoms and medical history.
Common Conditions Monitored
This test is often used to diagnose hereditary angioedema or to check for conditions affecting protein levels in the blood, such as liver disease or kidney problems.
Reference range
Negative: <0.35 kU/L; Equivocal: 0.35-0.69 kU/L; Positive: ≥0.70 kU/L. Results indicate presence or absence of IgE antibodies specific to Aspergillus niger in serum.N/A
No fasting required. No special patient preparation needed. Patients should inform their healthcare provider of any current antihistamine or corticosteroid use, as these medications may affect IgE levels but generally do not prevent antibody detection.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Serum Angiotensinogen
Frequently asked questions
How often will I need this test?
What are the typical reference ranges?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy