Angiotensinogen (Serum)
This test measures the level of angiotensinogen, a protein in your blood that helps regulate blood pressure by influencing the production of angiotensin II, a hormone that constricts blood vessels.
["Angiotensinogen helps control your blood pressure and may be checked if you have conditions like hypertension or kidney disease."]
Key facts at a glance
- LOINC
- 6830-4
- Short code
- ASPNIGER
- Synonyms
- A niger IgE Qn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top serum tube or serum separator tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 0.35
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunoassay (Fluorescent Enzyme Immunoassay or Chemiluminescent Immunoassay)
- CPT
- 86003
- SNOMED
- 395140002
- Specimen volume
- 1-2 mL serum
- Stability
- Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have symptoms of high blood pressure, kidney problems, or if you’re being evaluated for conditions like polycystic kidney disease (PKD) or certain types of kidney failure. It may also be done as part of a broader evaluation for inherited disorders affecting blood pressure regulation.
What to Expect Before the Test
No special preparation is usually needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re on blood thinners, let your provider know before the test.
What the Results Mean
Results can vary based on individual health and may not have a single standard range. High levels might suggest certain genetic conditions, while low levels could be linked to kidney disease or other metabolic issues. Your provider will interpret results in the context of your overall health.
Common Conditions Monitored
Angiotensinogen levels are often checked in people with suspected inherited disorders like **hyperangiotensinogenemia**, kidney diseases, or those with unexplained high blood pressure. It may also be part of a screening for conditions affecting blood vessel function.
Reference range
Negative: <0.35 kU/L; Equivocal: 0.35-0.70 kU/L; Positive: >0.70 kU/L (Class 0-6 scoring system used; specific reference ranges may vary by laboratory and assay manufacturer)N/A
No special preparation required. Patient should inform clinician of all current medications, especially antihistamines or corticosteroids, which may affect IgE results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Angiotensinogen Level
Frequently asked questions
What might cause abnormal results?
How often should this test be repeated?
Can diet or lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy