Anti-IgG Immunoglobulin G Antibody (Serum)
This test measures the presence of antibodies against the IgG class of immunoglobulins in your blood. These antibodies may indicate an immune response to certain infections, autoimmune conditions, or other health factors.
["This test helps identify potential immune reactions or conditions affecting your immune system."]
Key facts at a glance
- LOINC
- 108119-9
- Short code
- ASPNIGG
- Synonyms
- A niger IgG Qn IA
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top clot tube; plasma may be collected in lithium heparin or EDTA tubes.
- Units
- N/A
- Ref low
- 0
- Ref high
- 27
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunoassay (e.g., ELISA, FEIA, or CLIA)
- CPT
- 86001
- SNOMED
- 395112001
- Specimen volume
- 0.5-1 mL serum or plasma
- Stability
- Serum/plasma stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–72 hours
- Order
- routine
What This Test Measures
Anti-IgG antibodies are part of your immune system’s defense. This test detects specific antibodies that target IgG, a type of protein found in blood and tissues. These antibodies can be produced in response to infections, vaccines, or autoimmune diseases.
Why It Might Be Ordered
Your healthcare provider may order this test if you have symptoms like fatigue, joint pain, or unexplained infections. It could also be used to monitor conditions such as autoimmune disorders, certain infections, or to check immune function after vaccination.
Common Uses in Healthcare
This test is often used to diagnose or monitor conditions like lupus, rheumatoid arthritis, or infections such as HIV, where IgG antibodies play a role. It may also be part of a broader immune evaluation.
Sample Collection and Preparation
A blood sample is collected from a vein in your arm. The sample is sent to a lab where it is processed to separate serum (the liquid part of blood without clotting factors). The test measures the concentration of antibodies against IgG.
Reference range
Reference range varies by assay manufacturer; generally, results are interpreted qualitatively (negative/positive) or semi-quantitatively. Negative or < 27 mg/L (or equivalent units) typically considered negative. Consult laboratory-specific reference range.N/A
No special preparation required. Specimen collection is not affected by fasting status.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Anti-IgG
Frequently asked questions
How does this test help doctors diagnose or manage health conditions?
What do abnormal results mean?
Can lifestyle or diet affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy