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Antigen IgE to *Nematoda* (e.g., *Anisakis* species) - Serum

Published: August 9, 2026Updated: August 15, 2026

This test measures your immune system’s response to parasitic worms, such as those from the *Anisakis* genus, which can sometimes infect the digestive tract or other organs. It helps identify if your body has produced antibodies against these organisms.

Quick summary

["This test may help diagnose infections or allergic reactions to certain parasitic larvae."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
10919-9
Short code
ANISIGE
Synonyms
Anisakis IgE Qn
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube with clot activator
Units
N/A
Ref low
0.35
Ref high
0.69
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Fluorescent Enzyme Immunoassay or Chemiluminescent Immunoassay)
CPT
86003
SNOMED
395112001
Specimen volume
0.5-1 mL serum
Stability
Stable at room temperature for 8 hours; refrigerated (2-8°C) for 7 days; frozen (-20°C or below) for up to 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What This Test Measures

The test detects levels of Immunoglobulin E (IgE), a type of antibody your immune system produces in response to allergens or parasites. Elevated IgE levels toward *Anisakis* larvae may suggest exposure or an allergic reaction.

Why It’s Done

Your healthcare provider may order this test if you’ve experienced symptoms like stomach pain, nausea, vomiting, or allergic reactions (e.g., hives, swelling) after eating raw or undercooked seafood. It can also be used in research or specialized diagnostic settings for parasitic infections.

What to Expect

A blood sample will be drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The test involves sending your serum to a lab for analysis.

Possible Results

Results can be either positive (indicating some immune response) or negative (no detectable IgE). High levels may suggest past exposure or an allergic reaction, but they don’t always confirm an active infection. Interpretation depends on clinical context.

Reference range

Negative: <0.35 kU/L; Equivocal: 0.35-0.69 kU/L; Positive: 0.70-3.49 kU/L; Strongly Positive: ≥3.50 kU/L. Reference values may vary by laboratory and assay manufacturer.N/A

Specimen: serum

No special preparation required. Patients should inform their healthcare provider of any antihistamine or corticosteroid use, as these may affect IgE levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgE to Parasitic Larvae

Frequently asked questions

How often should I get this test?
This test isn’t routinely recommended for most people. It’s typically ordered based on symptoms, a history of parasitic exposure, or specific clinical needs (e.g., research studies). Follow your healthcare provider’s guidance for timing.
What do elevated IgE levels mean?
Elevated IgE levels toward *Anisakis* larvae may indicate an allergic reaction or past exposure, but they don’t always mean you have an active infection. Symptoms like vomiting or allergic reactions should be discussed with your doctor.
Can this test detect active infection?
No, this test measures antibodies (IgE) produced by your immune system in response to exposure. It doesn’t directly detect live parasites or active infection. Other diagnostic methods (e.g., stool exams, imaging) may be needed for confirmation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy