Skip to content

Alpha-Hydroxyetizolam/Creatinine, Calculated Ratio

Published: August 9, 2026Updated: August 16, 2026

Compares the alpha-hydroxyetizolam metabolite with creatinine, which can help account for differences in sample concentration when assessing etizolam exposure.

Quick summary

["A measurable result may indicate recent etizolam use, but it must be interpreted with timing, medication history, and other findings."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101155-0
Short code
A-OH-etizolam/Creat Ur Cfm
Synonyms
A-OH-etizolam/Creat Ur Cfm
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures alpha-hydroxyetizolam, a metabolite of the benzodiazepine etizolam, relative to the amount of creatinine in the same sample. Creatinine is commonly used as a reference to help reduce the effect of differences in sample concentration.

Why might I need this test?

This measurement may be used to evaluate suspected benzodiazepine exposure, often as part of toxicology or medication-monitoring testing. It may be requested by a clinician, workplace program, or other authorized screening program.

How is the test performed?

A laboratory sample is analyzed to determine the amount of alpha-hydroxyetizolam and creatinine. The laboratory then calculates and reports the ratio of one measurement to the other.

How do I prepare for the test?

No special preparation is generally required for this calculated test. Follow the laboratory's sample-collection instructions, and tell the clinician about medicines or supplements you have recently taken.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Alpha-Hydroxyetizolam/Creatinine Ratio

Frequently asked questions

What does alpha-hydroxyetizolam show?
It is a metabolite formed when the body processes etizolam. Detecting it can provide evidence of recent etizolam exposure.
Why is the result compared with creatinine?
Creatinine is used as an internal reference that can help account for how concentrated or dilute a sample is. The ratio is generally more useful than the metabolite measurement alone.
Does a positive result mean I was impaired?
No. A positive result indicates that exposure or metabolism was detected, but it does not by itself establish when the drug was taken or whether impairment was present.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy