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Antibody to *Streptococcus* Group A (ASO) by Immunofluorescence

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies in your blood that your immune system produces in response to *Streptococcus* Group A bacteria, often linked to infections like strep throat or skin infections.

Quick summary

["Detects past or current strep infections that your body may have fought off."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29208-6
Short code
ASO Ab Fld-aCnc
Synonyms
ASO Ab Fld-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The ASO test identifies antibodies (specifically anti-streptolysin O) that your immune system creates after exposure to *Streptococcus* Group A bacteria. These antibodies can remain in your blood for months or even years after the infection has cleared, helping your body remember the threat for future protection.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like sore throat, fever, rash, or joint pain that could suggest a strep infection. It’s also used to confirm a diagnosis when other tests (like rapid strep swabs) are inconclusive or if you’ve had recurrent infections.

What to Expect Before the Test

No special preparation is needed. You may have a simple blood draw from a vein in your arm, similar to other routine blood tests. If you’re concerned about needles, let your healthcare provider know so they can offer comfort measures.

What to Expect After the Test

After the blood is drawn, you may feel a slight pinch or bruising at the site, which usually fades within a day. There are no major side effects, but if you experience excessive bleeding or pain, contact your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive ASO test indicates your body has mounted an immune response to *Streptococcus* Group A, which can help diagnose past infections like scarlet fever, rheumatic fever, or post-streptococcal glomerulonephritis. However, it’s not always definitive for active infections, so your provider may combine results with other tests or symptoms to guide treatment.

Short name

ASO Antibody Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
What does a high or low ASO level mean?
A high ASO level suggests your body has been exposed to *Streptococcus* Group A bacteria at some point, but it doesn’t always indicate an active infection. A low or negative result means your body likely hasn’t produced these antibodies recently, though it could still have been exposed earlier.
Can I take antibiotics before getting this test?
Yes, if you’re prescribed antibiotics for a suspected strep infection, you should take them before testing, as they may lower your ASO levels. Always follow your provider’s instructions for timing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy