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Anti-Streptolysin O (ASO) Antibody, Titration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to certain bacteria, specifically *Streptococcus pyogenes* (Group A Streptococcus). It helps identify past or recent infections.

Quick summary

["ASO helps diagnose or monitor strep throat or rheumatic fever caused by group A strep bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110759-8
Short code
ASO Ab Msmt Ser
Synonyms
ASO Ab Msmt Ser
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Used For?

Doctors use ASO testing primarily to diagnose **Group A Streptococcus (GAS) infections**, such as strep throat, scarlet fever, or rheumatic fever. It can also help determine if you’ve had a recent strep infection, even if symptoms have cleared. ASO levels rise after infection and may stay elevated for months, so it’s useful for tracking long-term exposure or recurrence.

How Is the Sample Collected?

A blood sample is drawn from a vein in your arm by a healthcare professional. You may feel a brief pinch, but it usually doesn’t cause discomfort. The blood is sent to a lab for testing.

What Does a High or Low ASO Level Mean?

A **high ASO level** suggests you’ve had a recent or past GAS infection. Very high levels may indicate rheumatic fever or other complications. A **low or normal ASO level** means either you haven’t been infected recently or the infection has cleared. Note that ASO testing isn’t definitive for active strep throat—other tests (like rapid strep swabs) may be needed for immediate diagnosis.

How Long Does It Take to Get Results?

Results are typically available within **1–3 business days**, depending on lab processing times. Your doctor will discuss the meaning of your results in relation to your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

ASO Antibody

Frequently asked questions

Why might my doctor order this test?
Your doctor may order ASO testing if you have symptoms like sore throat, fever, rash, or joint pain that could suggest strep infection or rheumatic fever. It’s also used in cases where symptoms don’t match typical strep throat or if you’ve had recurrent infections.
What if my ASO level is high but I don’t have symptoms?
A high ASO level can persist for months after infection, even if symptoms have resolved. It may indicate past exposure or a low-grade, chronic infection. Your doctor will consider other factors, like medical history, to guide treatment.
Can ASO testing replace other diagnostic tests?
No. ASO testing is a general marker for past GAS exposure. For immediate diagnosis of strep throat, rapid strep swabs or throat cultures are preferred. ASO helps confirm long-term infection risk or guide follow-up care, but it’s not a standalone diagnostic tool.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy