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Antibody to Streptococcus Group A (ASO) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to a bacterial infection caused by *Streptococcus group A* (commonly called Group A Streptococcus, or GAS). It helps identify past or recent infections that may have led to conditions like strep throat or rheumatic fever.

Quick summary

["This test helps doctors diagnose or monitor infections linked to Group A Streptococcus bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45228-4
Short code
ASO Ab Ser-mCnc
Synonyms
ASO Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like sore throat, fever, rash, or joint pain that could suggest a Group A Streptococcus infection. It may also be used to check if you’ve recovered from such an infection or to monitor complications like rheumatic fever.

What Does a Positive Result Mean?

A positive result indicates your body has produced antibodies against Group A Streptococcus, suggesting you’ve likely had an infection in the past. However, it doesn’t always mean you’re currently infected—some people may have lingering antibodies even after recovery.

What Does a Negative Result Mean?

A negative result means your body hasn’t produced detectable antibodies to Group A Streptococcus at this time, which could mean you’re not currently infected or haven’t been exposed recently.

How Is This Test Performed?

A blood sample is drawn from a vein in your arm. The sample is then tested in a lab to measure the concentration of ASO antibodies using an immunoassay method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is primarily used to diagnose or confirm a history of Group A Streptococcus infection, such as strep throat or scarlet fever. Elevated levels may also be associated with post-streptococcal complications like acute glomerulonephritis or rheumatic fever, though other tests may be needed to confirm these conditions.

Short name

ASO Antibody Test

Frequently asked questions

What Are the Common Symptoms of Group A Streptococcus Infection?
Common symptoms include sudden onset of sore throat, fever, red or swollen tonsils, white patches on the throat, swollen lymph nodes in the neck, and sometimes a rash (like scarlet fever). Some people may also experience joint pain or swelling.
How Long Does It Take to Get Results?
Results are typically available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can This Test Be Done at Home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home testing kits are not available for this specific test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy