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Antibody to Streptococcal Group A Bacteria (ASO) – Serum, Qualitative or Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies produced in response to Streptococcus group A bacteria, often linked to strep throat or other infections. It helps diagnose past or current infections and guides treatment decisions.

Quick summary

["Detects antibodies from strep infections to guide treatment and monitor recovery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30149-9
Short code
ASO Ab sp1 Ser-aCnc
Synonyms
ASO Ab sp1 Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The ASO test identifies antibodies (specifically anti-streptolysin O antibodies) your immune system makes when exposed to certain bacteria, such as those causing strep throat. These antibodies can remain in your blood for months or years after the infection has cleared.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like sore throat, fever, rash, or swollen lymph nodes, especially if strep throat is suspected. It can also help evaluate recurrent infections or assess complications like rheumatic fever.

How the Test Works

A blood sample is drawn from a vein in your arm. The serum is tested to detect the presence of ASO antibodies using an immunoassay method, which may involve detecting antibody levels through color change or other indicators.

What to Expect Before the Test

No special preparation is needed, but inform your provider about any medications, recent infections, or allergies. Avoid strenuous activity 24 hours before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated ASO levels suggest a recent streptococcal infection. While not always definitive, they support a diagnosis of strep throat or other streptococcal-related conditions. Persistently high levels may indicate chronic exposure or autoimmune conditions. Always consult your provider for interpretation.

Short name

ASO Antibody Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your provider will discuss findings during your follow-up visit.
Can I have this test if I’m pregnant?
Yes, this test is generally safe during pregnancy. However, always share your pregnancy status with your provider before the test to ensure it’s appropriate for your situation.
Does this test show if I currently have strep?
This test detects past infections by measuring antibodies. For active strep infections, a rapid strep test or throat culture may be used instead. Your provider will determine the best approach based on symptoms and clinical judgment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy