Aspartylglycosaminuria (AGU) protein glycosylation profile (serum/plasma)
This test measures how certain proteins in your blood are attached to sugar molecules, which can help diagnose or monitor aspartylglycosaminuria, a rare genetic disorder affecting protein processing.
["This test helps assess how well your body processes proteins linked to sugar molecules, useful for diagnosing or tracking genetic disorders like aspartylglycosaminuria."]
Key facts at a glance
- LOINC
- 79636-7
- Short code
- Aspartylglycosamine/Creat Ur-sRto
- Synonyms
- Aspartylglycosamine/Creat Ur-sRto
- Category
- glucose
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test evaluates the abnormal glycosylation pattern of specific proteins in your blood, which is characteristic of aspartylglycosaminuria. Normally, proteins are attached to sugars during production in cells. In AGU, this process is disrupted, leading to altered sugar attachments that can be detected in blood samples.
Why It’s Done
Your healthcare provider may order this test if you have symptoms of aspartylglycosaminuria, such as developmental delays, intellectual disability, or movement disorders. It may also be used in research or specialized genetic testing programs.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate the serum or plasma, which is then analyzed for glycosylation patterns using advanced laboratory techniques.
What to Expect Before the Test
No special preparation is typically needed, but you may be asked to avoid certain medications or foods that could interfere with results. Always follow your healthcare provider’s instructions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Aspartylglycosaminuria causes a buildup of abnormal proteins in the brain and other organs due to defective glycosylation. Early diagnosis can help manage symptoms through specialized diets, physical therapy, and monitoring. This test helps confirm the diagnosis by identifying the unique protein glycosylation pattern linked to AGU.
Short name
AGU Glycosylation Test
Frequently asked questions
What does this test detect?
How is the test performed?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy