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Vitamin E (Alpha-Tocopherol), Red Blood Cells — Substance Concentration

Published: August 9, 2026Updated: August 17, 2026

Measures vitamin E (alpha-tocopherol) in red blood cells to help assess vitamin E status and nutritional balance.

Quick summary

["This blood test measures vitamin E stored in red blood cells and may help identify deficiency or excess."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
74513-3
Short code
A-Tocopherol Vit E EntSub RBC
Synonyms
A-Tocopherol Vit E EntSub RBC
Category
liver
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures alpha-tocopherol, the main form of vitamin E, in red blood cells. Red blood cell vitamin E can help provide information about longer-term vitamin E status.

Why might I need this test?

A clinician may order this test when vitamin E deficiency or excess is suspected. It may be considered with symptoms of deficiency, poor dietary intake, conditions that affect fat absorption, or use of vitamin E supplements.

How is the test performed?

A blood sample is collected, and the laboratory measures alpha-tocopherol in the red blood cell component. The sample is then analyzed using a validated laboratory method.

How do I prepare for the test?

Special preparation is generally not required, but follow any instructions provided by the laboratory or your clinician. Tell your clinician about vitamin E supplements and other products you take because they may affect the result.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A low red blood cell vitamin E level may reflect inadequate dietary intake, impaired absorption or transport, certain chronic illnesses, or a rare inherited vitamin E deficiency. A high level may occur with excessive supplementation. Results should be interpreted with diet, supplement use, symptoms, and other laboratory findings.

Short name

Vitamin E, Red Blood Cells

Frequently asked questions

What does this test measure?
It measures vitamin E, specifically alpha-tocopherol, in red blood cells. This can provide information about vitamin E status over time.
How is it different from a serum vitamin E test?
The red blood cell measurement reflects vitamin E associated with cells over a longer period, while serum vitamin E can change more quickly. Your clinician may use either or both depending on the situation.
Can vitamin E supplements affect the result?
Yes. Supplements and other vitamin E products can raise the measured level, so disclose their use to your clinician before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy