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Alpha-Tocopherol (Vitamin E), Tissue — Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

Measures the amount of alpha-tocopherol, the main form of vitamin E, in a tissue specimen.

Quick summary

["This test measures tissue vitamin E and may help assess vitamin E status when blood testing is insufficient."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
20681-3
Short code
A-Tocopherol Vit E Tiss-mCnt
Synonyms
A-Tocopherol Vit E Tiss-mCnt
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
5
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures alpha-tocopherol, also called vitamin E, in a tissue sample. Alpha-tocopherol is the form of vitamin E that most effectively protects cells from oxidative damage.

Why might I need this test?

A clinician may order this test to evaluate vitamin E levels when there is concern about poor nutrition, inability to absorb dietary fat, or another condition that could affect vitamin E status.

How is the test performed?

A laboratory analyzes the tissue specimen provided by your clinician and measures the concentration of alpha-tocopherol. The result is reported as a mass concentration.

How do I prepare for the test?

No special preparation is generally required for the tissue measurement itself. If a biopsy or surgical sample is needed, your clinician will explain the collection procedure and any specific instructions.

Reference range

NCBI: Vitamin E 5-20 µg/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Tissue Vitamin E

Frequently asked questions

What does alpha-tocopherol measure?
It measures the main active form of vitamin E in the tested specimen. Vitamin E helps protect cells from oxidative damage and supports immune and nervous system function.
Why is tissue vitamin E tested instead of blood vitamin E?
Tissue testing may occasionally be used when blood results do not adequately answer the clinician's question or when a tissue sample is already available. Blood vitamin E testing is generally more common.
Do I need to stop taking vitamin E supplements?
Do not stop prescribed supplements without medical advice. Tell your clinician about all vitamin E supplements and doses so the result can be interpreted safely.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy