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Water-Soluble Contrast in Random Fluid — Post-procedure

Published: August 9, 2026Updated: August 16, 2026

Detects water-soluble contrast material in a collected body fluid after a procedure, usually to evaluate for leakage or an abnormal connection.

Quick summary

["Finding contrast in the fluid may indicate leakage or an abnormal passage from the organ that received the contrast."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86422-3
Short code
AXR and Flr UGI W H2O soluble contr PO
Synonyms
AXR and Flr UGI W H2O soluble contr PO
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xr-rf
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test checks a body-fluid specimen for water-soluble contrast material that was administered during an imaging or surgical procedure. It is generally used to identify a leak or an abnormal connection involving the organ that received the contrast.

Why might I need this test?

The test may be ordered after imaging or surgery if there is concern that contrast has entered an unexpected body cavity or fluid space. Depending on the procedure and fluid involved, it can help evaluate for leakage, a fistula, or an unintended connection between organs.

How is the test performed?

A clinician collects an appropriate fluid specimen, often during or shortly after the related procedure. The laboratory examines the specimen for contrast material using validated testing methods. The result is interpreted together with the procedure performed and the fluid source.

How do I prepare for the test?

No special preparation is usually required when the specimen is collected during another procedure. If you are instructed to provide the specimen yourself, follow the collection instructions exactly and tell the healthcare team about any recent imaging or contrast administration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detecting water-soluble contrast in an unexpected body fluid may indicate leakage from the contrast-filled organ or an abnormal connection between organs. A positive finding can support the diagnosis of a fistula, perforation, or procedure-related leak. Interpretation depends on the fluid type, collection time, and procedure because contrast may also be present for expected reasons, such as shortly after surgery.

Short name

Water-soluble contrast in fluid

Frequently asked questions

What does a positive result mean?
It means water-soluble contrast material was detected in the tested fluid. In the appropriate clinical setting, this may suggest leakage or an abnormal connection between the organ that received the contrast and the fluid collection site.
Does a negative result rule out a leak?
Not always. The amount of contrast present, the time between the procedure and collection, and the type of fluid collected can affect detection, so the result must be interpreted with the procedure and imaging findings.
Is this the same as a blood test for kidney function after contrast?
No. This test examines a body-fluid specimen for contrast material, whereas contrast-related kidney function tests usually measure substances such as creatinine in blood.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy