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Beta-2-glycoprotein I (Anti-Cardiolipin) Antibody, Immunoassay (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against a specific protein found in your blood, called beta-2-glycoprotein I. These antibodies may be linked to certain autoimmune conditions or blood clotting issues.

Quick summary

["Your results help doctors check for possible autoimmune or clotting disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44447-1
Short code
B2 Glycoprot1 IgA SerPl IA-aCnc
Synonyms
B2 Glycoprot1 IgA SerPl IA-aCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like unexplained fatigue, joint pain, or a history of blood clots. It’s also sometimes used to monitor conditions like lupus or other autoimmune diseases.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Higher-than-normal levels may suggest an autoimmune response or increased risk of clotting. Lower levels are usually normal. Your doctor will discuss results in the context of your overall health.

Common Conditions Linked to This Test

Elevated results can be associated with conditions like antiphospholipid syndrome (APS), lupus, or other autoimmune disorders. It’s not a standalone diagnosis but part of a broader evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Autoimmune and Thrombosis Monitoring

Short name

Anti-Cardiolipin Antibody (IgG)

Frequently asked questions

How often will I need this test?
Your doctor will determine how often you need retests based on your symptoms, medical history, and treatment plan. Some patients may need it yearly or as needed for monitoring.
Can I eat or drink before this test?
You can eat and drink normally unless your doctor specifies otherwise. This test only requires a blood draw, so fasting isn’t required.
Will this test affect my medications?
This test itself won’t change your medications, but high or low results may influence treatment decisions. Always follow your doctor’s advice regarding any changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy