Serum β2-glycoprotein I (β2-GPI) Immunoglobulin G (IgG) Antibody Level
This test measures the level of antibodies against β2-glycoprotein I (β2-GPI) in your blood. β2-GPI is a protein involved in blood clotting and inflammation, and antibodies against it may be linked to certain autoimmune conditions.
["This test helps assess potential autoimmune risks, including antiphospholipid syndrome."]
Key facts at a glance
- LOINC
- 16136-4
- Short code
- B2 Glycoprot1 IgM Ser-aCnc
- Synonyms
- B2 Glycoprot1 IgM Ser-aCnc
- Category
- glucose
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained blood clots, recurrent miscarriages, or other signs of autoimmune disorders. It may also be part of a broader evaluation for conditions like lupus or other connective tissue diseases.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood from a vein. The process is quick and usually painless. If you’re nervous, let your healthcare provider know so they can provide reassurance or additional support.
What the Test Results Mean
Results are qualitative (positive or negative) rather than numeric. A positive result means your blood contains antibodies against β2-GPI, which may indicate an increased risk of autoimmune-related clotting issues. Your provider will discuss these findings in detail with you.
Common Conditions Linked to Positive Results
Positive antibody levels are often associated with antiphospholipid syndrome (APS), a condition where the immune system mistakenly attacks blood clots. Other conditions that may be linked include lupus, thrombocytopenia, and other autoimmune diseases.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used to identify the presence of antibodies that may contribute to blood clotting problems or other autoimmune reactions. While a positive result can raise concerns, it doesn’t diagnose a specific condition alone. Your healthcare provider will consider the results alongside your symptoms, medical history, and other tests to guide further evaluation.
Short name
β2-GPI IgG Antibody
Frequently asked questions
What does a positive result mean for my health?
Will I need to take any special steps if my test is positive?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy