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B2-Glycoprotein I Immunoglobulin Level (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of B2-glycoprotein I, a protein found in your blood that may be linked to certain autoimmune conditions.

Quick summary

["Understanding your B2-glycoprotein I levels can help assess potential autoimmune activity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43916-6
Short code
B2 Glycoprot1 IgM Ser Ql
Synonyms
B2 Glycoprot1 IgM Ser Ql
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or conditions associated with autoimmune disorders, such as antiphospholipid syndrome (APS), or if you are being monitored for known B2-glycoprotein I-related issues. It can also be part of a broader evaluation for thrombotic events or other systemic conditions.

What Does This Test Involve?

A blood sample is drawn from a vein, usually in your arm. The sample is processed to measure the concentration of B2-glycoprotein I in your serum.

What Do Results Mean?

Results are typically reported as a concentration value (e.g., in grams per liter). While reference ranges can vary by lab, elevated or altered levels may suggest increased autoimmune activity or other underlying conditions. Your provider will interpret results in the context of your medical history and symptoms.

Common Conditions Monitored

This test is often used to monitor patients with antiphospholipid syndrome (APS), a condition where the immune system mistakenly attacks proteins in the blood, potentially leading to blood clots. It may also be part of investigations for other autoimmune or inflammatory conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

B2-Glycoprotein I IgG

Frequently asked questions

What does a high or low B2-glycoprotein I level indicate?
High levels or abnormal binding patterns may indicate an increased risk of autoimmune-related clotting disorders or other inflammatory conditions. Low levels alone may not have direct clinical significance unless part of a broader evaluation.
How often should this test be repeated?
Your healthcare provider will determine the frequency based on your medical needs, symptoms, and treatment plan. Follow-up may be scheduled periodically if you are being monitored for conditions linked to B2-glycoprotein I.
Can lifestyle changes affect B2-glycoprotein I levels?
While lifestyle factors like diet and exercise can influence overall health, there is limited evidence that they directly impact B2-glycoprotein I levels. Your provider will discuss any potential influences based on your specific situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy