Beta-2 Microglobulin (Mass Concentration)
This test measures the level of beta-2 microglobulin, a small protein found in the blood that can help assess kidney function and certain immune system conditions.
["Beta-2 microglobulin levels may indicate kidney health or immune-related disorders."]
Key facts at a glance
- LOINC
- 83077-8
- Short code
- UB2MG
- Synonyms
- B2 Microglob Ur IA-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile, plastic, leak-proof urine container
- Units
- N/A
- Ref low
- 0
- Ref high
- 300
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunoassay
- CPT
- 82232
- SNOMED
- 313803006
- Specimen volume
- 10 mL random or 24-hour urine collection
- Stability
- Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C. Adjust pH to >6.0 with sodium hydroxide if not analyzed within 24 hours to prevent degradation of beta-2-microglobulin.
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Doctors may order this test to evaluate kidney function, especially in people with chronic kidney disease or other conditions affecting the kidneys. It can also help monitor immune system disorders, such as certain types of arthritis or cancers like multiple myeloma.
What Does the Result Mean?
Higher than expected levels may suggest kidney problems or conditions affecting protein breakdown in the body. Lower levels might be less common but could indicate certain genetic or metabolic issues. Your healthcare provider will interpret results in the context of your overall health and medical history.
Sample Collection and Preparation
A blood sample is typically taken from a vein in your arm. The blood is collected in a special tube that prevents clotting. This test requires no special preparation, but you may be asked to fast for a few hours before the test if instructed by your doctor.
Common Conditions Monitored
This test is often used in the monitoring of chronic kidney disease, immune system disorders like rheumatoid arthritis, and conditions such as multiple myeloma or other hematologic malignancies.
Reference range
Typically <300 µg/L; clinical interpretation requires comparison with serum beta-2-microglobulin and assessment of renal tubular functionN/A
No fasting required. Patient should maintain normal hydration prior to collection. Avoid vigorous exercise before specimen collection as it may affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Beta-2 Microglobulin
Frequently asked questions
What causes beta-2 microglobulin levels to be higher than normal?
Can diet affect beta-2 microglobulin test results?
How often should this test be repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy