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IgM Antibody to *Babesia* (Serum/Plasma)

Published: August 9, 2026Updated: August 15, 2026

This test measures antibodies in your blood that your immune system produces in response to an infection by *Babesia*, a type of parasite found in ticks. It helps diagnose early or recent infection.

Quick summary

["This test helps detect if you’ve been recently infected with *Babesia* by checking for early immune system response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
110796-0
Short code
BABIGM
Synonyms
Babesia IgM Msmt Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube
Units
N/A
Ref low
16
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Immunofluorescence Assay (IFA) or Enzyme Immunoassay (EIA)
CPT
86753
SNOMED
122500008
Specimen volume
1-2 mL of serum (minimum 0.5 mL)
Stability
Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What This Test Measures

The IgM antibody test looks for a specific type of antibody (IgM) that your body makes shortly after exposure to *Babesia*. IgM antibodies typically appear within weeks of infection and can persist for months. This test is often used alongside other tests to confirm a diagnosis, especially in cases where symptoms overlap with other illnesses.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like fever, chills, fatigue, or anemia, and suspect you’ve been exposed to ticks or live in an area where *Babesia* infections are common. It’s also used in cases where other blood tests (like those for malaria or anemia) don’t clearly explain your symptoms.

How the Test Works

A small blood sample is taken from your arm and sent to a lab. The lab uses an immunoassay method to detect IgM antibodies against *Babesia* in your serum or plasma. This process identifies whether your immune system has recognized the parasite.

What to Expect Before the Test

No special preparation is needed for this test. You may have a slight bruise or soreness at the injection site, but this usually goes away quickly. If you’re on blood-thinning medication or have a bleeding disorder, let your provider know before the test.

Reference range

Negative: <1:16 titer (IgM antibodies not detected); Equivocal: 1:16-1:32; Positive: ≥1:64. Reference range varies by laboratory and should be interpreted in conjunction with clinical findings, exposure history, and confirmatory testing.N/A

Specimen: serum

No special patient preparation required. Fasting is not necessary. Patients should inform their healthcare provider about recent tick exposure, travel history to endemic areas (northeastern and midwestern United States), blood transfusion history, or immunocompromised status, as these factors influence result interpretation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results suggest recent *Babesia* infection, which can cause severe illness, including kidney failure, neurological problems, or chronic fatigue. Early detection and treatment with appropriate antibiotics can improve outcomes. However, false positives may occur, so results are often confirmed with additional tests or clinical correlation. This test is most useful for diagnosing early or acute infection, not chronic disease.

Short name

IgM Antibody to Babesia

Frequently asked questions

How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I have this test if I’m pregnant?
Yes, this test is generally safe during pregnancy. However, always inform your healthcare provider about any medications you’re taking or health conditions you have before the test to ensure the best care.
What if my test results are positive?
If your IgM antibody test is positive, your provider may recommend additional tests (like PCR or blood smear) to confirm the diagnosis. Treatment with antibiotics (such as clindamycin or azithromycin) may be needed, depending on the severity of your symptoms and lab findings. Follow-up care with a specialist, like an infectious disease doctor, may be necessary.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy