Baboon Anti-Human IgG Immunoassay (Serum) with Screening and Confirmation
This test detects antibodies in your blood that may react with human immunoglobulin G (IgG) proteins, often used in blood compatibility screening or rare disease diagnostics.
["This test helps assess potential immune responses to human proteins, useful in blood transfusions or specific medical conditions."]
Key facts at a glance
- LOINC
- 71715-7
- Short code
- BRUCG12
- Synonyms
- B abortus IgG1+IgG2 Ser Ql IA
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top vacuum tube; sterile cryovial acceptable for aliquots
- Units
- N/A
- Ref low
- 0
- Ref high
- 1
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Immunoassay (Enzyme-Linked Immunosorbent Assay)
- CPT
- 86622
- SNOMED
- 122620004
- Specimen volume
- 1-2 mL serum (minimum 0.5 mL); collect 5-10 mL whole blood in appropriate tube
- Stability
- Serum stable at room temperature for 8 hours; refrigerated (2-8°C) for 7 days; frozen at -20°C or below for up to 30 days; avoid repeated freeze-thaw cycles
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–96 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you’re receiving blood transfusions to ensure compatibility, if you have a suspected autoimmune reaction, or if you’re being evaluated for conditions like autoimmune diseases or certain infections that involve antibody cross-reactivity with human proteins.
What to Expect Before the Test
No special preparation is typically needed. You may have a blood sample drawn from a vein in your arm. If you’re undergoing a transfusion, this test may be part of a routine pre-transfusion screening process.
What the Test Measures
This test measures the presence of antibodies in your serum that can bind to human IgG proteins. The test uses immunoassay methods to detect these antibodies, which may be qualitative (present or absent) or confirmatory (more detailed detection).
Possible Results and Their Implications
A positive result indicates the presence of antibodies that may react with human IgG, which could affect blood compatibility or suggest an underlying immune response. A negative result means no detectable antibodies were found in this test.
Reference range
Negative: IgG1 <1:100 and IgG2 <1:100; Positive: IgG1 ≥1:100 or IgG2 ≥1:100. Results reported as Detected or Not Detected with titer values for IgG1 and IgG2 subclasses.N/A
No special preparation required. Patient should inform provider of any recent antibiotic therapy, vaccination history (including Brucella vaccination), and occupational exposure risks (e.g., livestock handling, veterinary work, laboratory exposure).
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used in clinical settings to ensure safe blood transfusions by identifying potential immune reactions. It may also be used in research or rare disease diagnostics where antibody cross-reactivity is a concern. Results should always be interpreted by a healthcare provider in the context of your medical history and symptoms.
Short name
Anti-Human IgG Screening/Confirmation Test
Frequently asked questions
What does a positive result mean?
The frequency of this test depends on your medical condition and the reason it was ordered. Some patients may need it only once, while others may require it periodically, especially if they’re undergoing blood transfusions or have conditions that affect their immune response.
What are the risks or side effects of this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy