Beta-human chorionic gonadotropin (β-hCG) concentration in serum
This test measures the level of beta-human chorionic gonadotropin (β-hCG), a hormone produced during pregnancy. It helps confirm pregnancy and monitor its progress.
["A β-hCG test is critical for early pregnancy detection and evaluation."]
Key facts at a glance
- LOINC
- 22924-5
- Short code
- BRUCG1
- Synonyms
- B abortus IgG1 Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme-linked immunosorbent assay (ELISA)
- CPT
- 86622
- SNOMED
- 122450008
- Specimen volume
- 1-2 mL of serum
- Stability
- Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–72 hours
- Order
- routine
Why is this test done?
Your healthcare provider may order a β-hCG test if you suspect you are pregnant, have missed a menstrual period, or are experiencing early pregnancy symptoms like nausea or breast tenderness. It can also be used to check for ectopic pregnancy, miscarriage, or other pregnancy complications.
What does a β-hCG test involve?
A blood sample is taken from a vein in your arm. The sample is sent to a lab where it is analyzed to measure the amount of β-hCG in your serum. The test is typically done in the early stages of pregnancy but can also be used later to monitor hormone levels.
What might abnormal results mean?
Low β-hCG levels may indicate an early miscarriage, ectopic pregnancy, or a non-pregnant state. Very high levels might suggest a multiple pregnancy (twins, triplets) or other conditions. Your healthcare provider will discuss results with you based on your medical history and symptoms.
How is the test performed?
The test is a simple blood draw. You may feel a slight pinch when the needle is inserted, but it usually takes only a few minutes. You can resume normal activities afterward.
Reference range
Negative: IgG1 antibodies not detected; Positive: IgG1 antibodies detected, suggesting past exposure or chronic infection with Brucella abortusN/A
No fasting required. Patients should inform their healthcare provider about any recent antibiotic use, as treatment may affect antibody levels.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: β-hCG is the hormone detected by pregnancy tests. It rises in the blood after implantation of a fertilized egg. Levels are typically measured in International Units per Liter (IU/L). Early in pregnancy, levels double approximately every 48 hours. Abnormal patterns may signal issues requiring further medical evaluation.
Short name
β-hCG Serum
Frequently asked questions
What does a positive β-hCG test mean?
How soon after conception can this test detect pregnancy?
Can lifestyle factors affect β-hCG levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy