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Antibody Screening for Anticardiolipin (IgG) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies called anticardiolipin in your blood, which may be linked to certain autoimmune conditions or blood clotting issues.

Quick summary

["Anticardiolipin antibodies can help identify potential risks for blood clots or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105809-8
Short code
CFR
Synonyms
Bac antimicro res CFR Ct Bld +
Category
chemistry
Sample
whole-blood
Container
Positive blood culture bottle (aerobic or anaerobic) transferred to a sterile, leak-proof molecular transport tube or cryovial
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87798
SNOMED
43491000
Specimen volume
1-3 mL of positive blood culture broth; minimum 0.5 mL
Stability
Stable at 2-8°C for up to 24 hours after blood culture positivity; for longer delays, freeze at -70°C to -80°C. Do not freeze at -20°C.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
2–8 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained blood clots, recurrent miscarriages, or signs of an autoimmune condition. It could also be part of a broader evaluation for conditions like lupus or thrombophilia.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. It usually takes a few minutes, and you may feel a brief pinch. Avoid heavy exercise or smoking for a few hours before your appointment.

What the Test Results Mean

Results are qualitative (positive or negative) and indicate whether your blood contains detectable levels of anticardiolipin antibodies. Elevated levels may suggest an increased risk for blood clots or autoimmune activity, but they don’t diagnose a specific condition alone.

Possible Follow-Up Actions

If your test is positive, your doctor may order additional tests or monitoring, such as checking for other autoimmune markers or evaluating your risk for clotting. They may also recommend lifestyle changes or medications to manage symptoms.

Reference range

Negative for cfr resistance gene. Cycle threshold (Ct) values are reported when positive; lower Ct values indicate higher bacterial load.N/A

Specimen: whole-blood

No special patient preparation required. Testing is performed on positive blood culture specimens, not direct patient draws.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Anticardiolipin Antibody (IgG) Screen

Frequently asked questions

What Does a Positive Result Indicate?
A positive result means your blood contains anticardiolipin antibodies, which may increase the risk of blood clots (thrombosis) or contribute to autoimmune diseases like lupus. However, not everyone with these antibodies will develop symptoms. Your doctor will assess your overall health and symptoms to guide next steps.
What Does a Negative Result Mean?
A negative result means your blood does not contain detectable anticardiolipin antibodies at this time. However, antibodies can fluctuate, so further testing may be needed if you have ongoing symptoms or risk factors.
Can This Test Be Used to Diagnose Autoimmune Diseases?
No, this test alone cannot diagnose autoimmune diseases like lupus or thrombophilia. It is often used as part of a broader evaluation, including clinical symptoms, other blood tests, and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy