Skip to content

What is a Colonoscopy?

Published: August 9, 2026Updated: August 17, 2026

A colonoscopy is a diagnostic procedure that lets your doctor closely examine the inner lining of your large intestine (colon) using a thin, flexible tube equipped with a small video camera.

Quick summary

{"A colonoscopy screens for colon cancer, polyps, and other digestive conditions","The procedure is typically performed under sedation for comfort","Preparation involves a special diet and bowel cleansing the day before","It is recommended for adults aged 45-75, or earlier if you have risk factors","The test usually takes 30-60 minutes and you can resume normal activities the next day"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
111829-8
Short code
COL
Synonyms
Background information Colonoscopy
Category
cardiac
Sample
serum
Container
Not applicable - this is a narrative procedure report
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
colonoscopy
CPT
45378
SNOMED
73761001
Specimen volume
Not applicable
Stability
Not applicable
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What is a Colonoscopy?

A colonoscopy is a medical procedure where a doctor uses a thin, flexible tube called a colonoscope to look inside your colon. The tube has a small camera on the end that sends images to a monitor, allowing the doctor to see the entire colon and rectum. During the procedure, the doctor can also remove polyps (abnormal growths) and take tissue samples if needed.

Why is This Test Performed?

Colonoscopies are primarily used to: (1) Screen for colon cancer, which is one of the most common cancers worldwide; (2) Detect and remove polyps before they become cancerous; (3) Investigate symptoms like rectal bleeding, chronic diarrhea, abdominal pain, or unexplained weight loss; (4) Monitor patients with a family history of colon cancer or inflammatory bowel disease.

How to Prepare for the Procedure

Proper preparation is essential for an accurate examination. You will need to: (1) Follow a special diet 1-3 days before - typically clear liquids only the day before; (2) Take bowel-cleansing medications (laxatives) as prescribed to empty your colon; (3) Inform your doctor about medications you take, especially blood thinners; (4) Arrange for someone to drive you home after the procedure since you will receive sedation.

What Happens During the Test?

You will lie on your side while the doctor inserts the colonoscope through your rectum and slowly advances it through your colon. Air is pumped in to expand the colon for better viewing. The procedure usually takes 30-60 minutes. You will be given sedatives to minimize discomfort. If polyps are found, they are typically removed during the procedure and sent to a laboratory for analysis.

After the Procedure

You will rest in a recovery area until the sedation wears off, usually 30-60 minutes. You may feel bloated or have gas cramps due to the air used during the procedure - this is normal and should resolve within a few hours. You can resume your normal diet the same day, though it's best to avoid heavy meals initially. If any tissue samples were taken or polyps removed, your doctor will discuss the results with you in a follow-up appointment.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

Patients must complete bowel preparation as instructed. Inform patient about procedure risks, benefits, and obtain informed consent. Discontinue anticoagulants as directed by physician. Maintain clear liquid diet day before procedure. No solid food after midnight prior to colonoscopy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Colonoscopy is considered the gold standard for colorectal cancer screening. It can detect cancer at early, treatable stages and allows for immediate removal of precancerous polyps. Regular colonoscopies can reduce the risk of dying from colon cancer by up to 70%. The procedure also helps diagnose inflammatory bowel diseases, diverticulosis, and other colon conditions. Early detection through colonoscopy significantly improves treatment outcomes and survival rates.

Frequently asked questions

Is a colonoscopy painful?
Most patients experience minimal discomfort during the procedure due to sedation medications. You may feel some bloating, gas, or mild cramping afterward, but these sensations typically subside within a few hours.
How often do I need a colonoscopy?
For most adults, screening is recommended every 10 years starting at age 45. However, if polyps are found or you have certain risk factors, your doctor may recommend more frequent examinations, such as every 3-5 years.
What are the risks of colonoscopy?
Complications are rare but can include bleeding (especially after polyp removal), perforation (tear) of the colon, and reactions to sedation. The risk of serious complications is less than 1% in most cases.
Can I resume normal activities after the procedure?
You should rest for the remainder of the day after your colonoscopy. Most people return to normal activities the following day. Avoid driving, operating machinery, or making important decisions for 24 hours due to the sedation.
What if polyps are found during my colonoscopy?
Finding polyps is actually the goal of screening - most polyps are benign (non-cancerous). Your doctor will remove them during the procedure and send them for laboratory analysis. If cancerous cells are found, your doctor will discuss treatment options with you.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy