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Understanding Your Laboratory Test: A Patient's Guide to Testing, Sample Collection, and Results

Published: August 9, 2026Updated: August 16, 2026

This test detects and identifies bacteria that are resistant to carbapenem antibiotics, which are powerful antibiotics used to treat serious infections.

Quick summary

{"Identifies bacteria resistant to carbapenem antibiotics","Helps doctors choose effective antibiotics for treatment","Important for infection control in healthcare settings","Results typically available in 2-5 days","Sample is collected from the infected area"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94151-8
Short code
CRB-ISO
Synonyms
Bacteria.carbpm resist Spec Cult
Category
chemistry
Sample
serum
Container
Sterile, leak-proof, wide-mouth container with secure screw-cap lid for tissue, fluid, or wound specimens; sterile swab transport system (Amies or Stuart transport medium, e.g., Copan ESwab or BD ESwab) for swab specimens; sterile blood culture bottles for blood specimens; sterile container with no preservatives for urine.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
organism-specific-culture
CPT
87081; 87184 (for carbapenem susceptibility if culture positive); 87150 (for carbapenemase PCR if performed); 87181 (for organism identification)
SNOMED
445980006 | Microorganism identified in specimen (finding) | ; 1003721000119102 | Carbapenem-resistant Enterobacteriaceae (organism) |
Specimen volume
Variable by specimen source: 1-5 mL for sterile body fluids (CSF, pleural, synovial, peritoneal); 5-10 mL for blood per blood culture bottle set (aerobic and anaerobic); 10-50 mL midstream or catheterized urine; tissue samples 1-2 cm³ minimum in sterile saline or transport medium; rectal or perianal swabs saturated with specimen.
Stability
Room temperature (20-25°C): process within 2 hours for optimal bacterial viability. Refrigerated (2-8°C): process within 24 hours for urine; not recommended for most other specimen types. Frozen: not acceptable. Transport medium swabs stable up to 48 hours at room temperature per manufacturer's instructions.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–168 hours
Order
routine

This is a laboratory test performed on a sample collected from your body, such as blood, urine, or other body fluids, that helps your healthcare provider evaluate your overall health, screen for certain conditions, or monitor how well a treatment plan is working.

This test looks for bacteria that are resistant to carbapenem antibiotics. Carbapenems are strong antibiotics often used when other antibiotics don't work. When bacteria become resistant to these drugs, they are called carbapenem-resistant organisms (CRO). The test involves growing bacteria from your sample in a laboratory to see what type of bacteria is present and whether it can resist carbapenem antibiotics.

Your doctor may order this test as part of a routine checkup, to help find the cause of symptoms you are experiencing, to check how well an organ is functioning, or to follow a known condition and see whether your current treatment is working as expected.

Your doctor may order this test if you have a suspected bacterial infection that isn't responding to standard antibiotics. This test is especially important for patients in hospitals or long-term care facilities, as carbapenem-resistant bacteria can spread easily in these settings. The results help your doctor determine which antibiotics will be most effective to treat your infection.

A trained healthcare professional will collect the sample, most often by drawing a small amount of blood from a vein in your arm or by asking you to provide a urine specimen; the procedure is usually quick, causes only brief discomfort, and you can normally return to your regular activities right afterward.

The sample type depends on where the infection is located. It may include blood, urine, stool, sputum, wound tissue, or fluid from around a surgical site. For this test, serum (the liquid part of blood after it clots) is one of the sample types that may be collected. A healthcare professional will collect the sample using a sterile technique to prevent contamination.

Your results are compared with established reference ranges to show whether your values fall within expected limits; a result outside the normal range does not always mean you are ill, so your healthcare provider will review the findings with you, explain what they may indicate, and recommend any follow-up testing or treatment if needed.

A positive result means carbapenem-resistant bacteria were found in your sample. This information helps your doctor choose alternative antibiotics that can still treat the infection. A negative result means no carbapenem-resistant bacteria were found, which may allow your doctor to use standard antibiotics. Your doctor will interpret these results along with your symptoms and other test findings to plan your treatment.

Reference range

Negative for carbapenem-resistant bacteria. No carbapenem-resistant organism isolated. Reportable result: Organism identified (genus and species) along with carbapenem resistance status (susceptible, intermediate, or resistant per CLSI breakpoints) and carbapenemase production confirmed/not detected.N/A

Specimen: serum

No special fasting required. Patient should discontinue topical or systemic antibacterial agents, including carbapenems, for at least 24-48 hours prior to specimen collection when clinically feasible and directed by the ordering physician. Note all current antibiotic therapy on the requisition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Carbapenem-resistant bacteria are a major public health concern. They can cause severe infections that are difficult to treat, leading to longer hospital stays, higher medical costs, and increased risk of death. Identifying these resistant bacteria helps guide appropriate antibiotic therapy and implements necessary infection control measures to prevent spread to other patients. Common carbapenem-resistant bacteria include carbapenem-resistant Enterobacteriaceae (CRE), which are often called 'superbugs' due to their resistance to multiple antibiotics.

Frequently asked questions

How long does it take to get results?
Results typically take 2-5 days because the test requires growing bacteria in a laboratory, which takes time. The bacteria need to multiply enough to be identified and tested for antibiotic resistance.
Is this test painful?
The discomfort level depends on the sample type. Blood collection may cause brief pain like a typical blood draw. Other sample collections (like urine or wound samples) may cause mild discomfort but are generally not painful.
What happens if the test is positive?
If carbapenem-resistant bacteria are found, your healthcare team will take extra precautions to prevent spread to others. You may be placed in isolation, and healthcare workers will use special protective equipment. Your doctor will prescribe different antibiotics that can still treat the infection.
Can family members get this type of infection?
Carbapenem-resistant bacteria can spread through direct contact with infected individuals or contaminated surfaces. Family members should follow good hand hygiene practices, especially when visiting healthcare facilities. The risk of transmission outside healthcare settings is generally lower but still possible.
Do I need to fast before this test?
Fasting is usually not required for this test. However, follow any specific instructions provided by your healthcare provider or testing facility.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy