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Understanding Your Diagnostic Laboratory Test: A Patient's Guide to Testing and Results

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of bacterial sialidase enzyme in your blood to help identify certain bacterial infections.

Quick summary

{"Bacterial sialidase is an enzyme produced by some harmful bacteria","This test uses a blood sample to check for infection markers","Results help doctors diagnose specific bacterial infections","The test is performed on serum (blood fluid)","Positive results indicate bacterial involvement"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41477-1
Short code
BSIAL
Synonyms
Bacterial sialidase Spec Ql
Category
chemistry
Sample
serum
Container
Sterile, leak-proof specimen container or transport medium appropriate for the specimen source
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Enzyme assay; colorimetric detection of sialidase (neuraminidase) enzymatic activity
CPT
87449
SNOMED
395086008
Specimen volume
1-2 mL of serum or appropriate specimen volume as required by testing laboratory
Stability
Refrigerate at 2-8°C and transport to laboratory within 24 hours; for extended storage, freeze at -70°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

This test is a diagnostic procedure that helps your healthcare provider evaluate how your body is functioning and identify possible medical conditions. It usually involves analyzing a small sample of blood, urine, or other tissue in a laboratory.

The bacterial sialidase test is a laboratory test that detects whether sialidase enzyme produced by bacteria is present in your blood specimen. Sialidase (also known as neuraminidase) is an enzyme that certain bacteria produce to help them invade and spread in the body. This test helps healthcare providers identify infections caused by sialidase-producing bacteria.

The test is typically performed in a clinic, hospital, or laboratory setting. A trained technologist will collect the required sample, often from a vein in your arm, and send it for analysis. The procedure is generally quick, and you can usually return to your normal activities right afterward.

A healthcare professional will collect a blood sample from a vein in your arm. The blood is then processed in a laboratory to separate the serum (the liquid part of blood). The serum is tested to detect the presence of bacterial sialidase enzyme using specialized laboratory methods.

Your doctor may order this test to help diagnose a medical condition, monitor an ongoing illness, check how well a treatment is working, or screen for health problems before symptoms appear. The results provide important information that helps guide your care plan.

Your doctor may order this test if you have symptoms of a bacterial infection, particularly when the infection involves areas where sialidase-producing bacteria are common, such as respiratory infections, bacterial vaginosis, or other infections. The test helps confirm whether specific bacteria are involved in your illness.

Your results will be compared against standard reference ranges. Values within the expected range suggest no abnormal findings, while results outside that range may point to a condition that needs further evaluation. Your healthcare provider will explain what your specific results mean and discuss any next steps with you.

A positive result means that bacterial sialidase was detected in your blood, suggesting that sialidase-producing bacteria are present and may be causing your infection. A negative result means no sialidase was detected, but this does not completely rule out infection—your doctor will interpret results together with your symptoms and other test findings.

Reference range

Negative (sialidase activity not detected). Result reported as Detected or Not Detected.N/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to initiation of antimicrobial therapy whenever possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Bacterial sialidase testing is clinically significant in diagnosing infections caused by bacteria that produce this enzyme, including certain strains of Gardnerella vaginalis (associated with bacterial vaginosis), Streptococcus pneumoniae, and other pathogenic bacteria. The presence of sialidase can indicate the severity of infection and help guide appropriate antibiotic treatment. This test aids in distinguishing bacterial infections from viral infections, as sialidase is specifically produced by bacteria.

Frequently asked questions

Do I need to fast before this test?
Typically, no fasting is required for this blood test. However, follow any specific instructions provided by your healthcare provider.
Are there any risks from the blood test?
The risks are minimal and include slight pain or bruising at the needle site, bleeding, or rarely, infection. These are common risks for any blood draw.
How long does it take to get results?
Results usually take 1-3 days, depending on the laboratory. Your healthcare provider will contact you with the results.
What happens if my test is positive?
If positive, your doctor will discuss treatment options, which typically include appropriate antibiotics targeting the specific bacteria causing the infection. Additional tests may be ordered to identify the exact bacteria.
Can this test diagnose bacterial vaginosis directly?
This blood test detects sialidase in serum, which can indicate systemic presence of sialidase-producing bacteria. For diagnosing bacterial vaginosis specifically, doctors often use vaginal swab tests rather than blood tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy