Understanding Your Medical Test: What It Is, How It Works, and Why Your Doctor May Have Ordered It
This test identifies the specific type of bacteria in a sample using DNA sequencing technology to guide targeted treatment.
{"Uses genetic sequencing to identify exact bacterial strain","Helps doctors choose the most effective antibiotics","Performed on a bacterial sample grown from your specimen","Provides more precise information than standard culture tests","Results help guide personalized treatment decisions"}
Key facts at a glance
- LOINC
- 91895-3
- Short code
- BSEQID
- Synonyms
- Bacterial strain Islt Seq
- Category
- chemistry
- Sample
- serum
- Container
- Sterile screw-cap cryovial or transport tube containing pure bacterial isolate on agar slant/plate or in liquid broth (e.g., tryptic soy broth)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 0 years
- Method
- sequencing
- CPT
- 87153
- SNOMED
- 104202003
- Specimen volume
- 1 mL liquid culture or one well-isolated colony on solid medium
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days for agar plates; Frozen (-80°C) in glycerol stock: 1-2 years
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 48–168 hours
- Order
- routine
This test is a medical evaluation that gathers important information about your health by measuring or examining specific markers, samples, or functions in your body. The results give your healthcare provider objective findings that help explain symptoms, confirm or rule out a condition, and guide the most appropriate plan of care for you.
Bacterial Strain Identification by Sequencing is a advanced laboratory test that identifies the specific type and strain of bacteria in a sample by analyzing its genetic material (DNA). Unlike standard culture tests that can only identify general categories of bacteria, this test uses sequencing technology to determine the exact bacterial strain, including antibiotic-resistant characteristics.
The test works by collecting a small sample or taking a measurement, such as blood, urine, or imaging, which is then analyzed using standardized laboratory or diagnostic methods. Trained professionals process the sample and compare your results against established reference ranges, producing findings your doctor can interpret alongside your medical history and current symptoms.
First, bacteria are grown from your sample (such as blood, urine, or tissue) in a laboratory. Then, the genetic material (DNA) is extracted from the grown bacteria and analyzed using sequencing technology. This genetic code is compared to databases of known bacterial strains to identify the exact type. The process can take several days to complete as it requires growing the bacteria first.
Your doctor may order this test for several reasons, including investigating symptoms you have reported, screening for conditions before they cause noticeable problems, monitoring an ongoing illness, or checking how well a treatment is working. The results help your care team make informed decisions, adjust medications when needed, and track changes in your health over time.
Your doctor may order this test when they need to know the exact identity of a bacterial infection. This is particularly important for: infections that are not responding to standard antibiotics, recurrent infections, serious infections requiring precise treatment, and outbreaks of infection where the source needs to be traced.
Reference range
Interpretive report provided; identification of bacterial strain type from submitted isolate.N/A
No patient preparation required. Collect bacterial isolate from pure culture on appropriate solid or liquid medium for submission to the sequencing laboratory.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test provides critical information for guiding treatment decisions. By identifying the exact bacterial strain, doctors can select the most appropriate antibiotic, especially for antibiotic-resistant bacteria. It also helps distinguish between bacterial and viral infections, preventing unnecessary antibiotic use. In outbreak situations, strain identification helps track how an infection is spreading and identify the source.
The test is particularly valuable for infections caused by bacteria that have developed antibiotic resistance, such as MRSA or ESBL-producing organisms. Understanding the specific strain helps healthcare providers choose effective treatments and implement appropriate infection control measures.
Frequently asked questions
How long does it take to get results?
Do I need to prepare for this test?
Is this test painful?
What do the results mean?
Are there any risks from this test?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy