Barbitalmsmtserpl
A barbital blood test measures the amount of this barbiturate medication in your blood to ensure safe and effective dosing.
{"Barbital is a long-acting sedative medication used to treat anxiety and sleep disorders","This test checks if the drug level in your blood is within the therapeutic range","Regular monitoring helps prevent toxicity and ensures proper dosing","Blood is typically drawn from a vein in your arm","Results help your doctor adjust your medication if needed"}
Key facts at a glance
- LOINC
- 109061-2
- Short code
- BARB
- Synonyms
- Barbital Msmt SerPl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top serum tube (no anticoagulant) or plasma separator tube (PST)
- Units
- N/A
- Ref low
- 2
- Ref high
- 10
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Gas Chromatography-Mass Spectrometry (GC-MS) or Immunoassay
- CPT
- 80299
- SNOMED
- 395152005
- Specimen volume
- 2 mL serum or plasma
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
What is this test?
The barbital blood test measures the concentration of barbital in your serum or plasma. Barbital is a barbiturate medication that has been used as a sedative and hypnotic agent. While less commonly prescribed today compared to newer medications, it may still be used in certain situations to manage anxiety, tension, and sleep disorders. This test helps healthcare providers ensure that patients are receiving the correct dose and are not at risk for toxicity.
Why is this test performed?
Your doctor may order this test for several reasons: to monitor therapeutic drug levels in patients taking barbital, to check for signs of overdose or toxicity, to evaluate suspected poisoning cases, to ensure medication compliance, or to help diagnose the cause of unexplained symptoms such as excessive drowsiness, confusion, or breathing problems. The test is also useful in forensic and emergency settings when barbital overdose is suspected.
How is the test done?
A healthcare professional will draw a blood sample from a vein in your arm using a small needle. The procedure only takes a few minutes and may cause slight discomfort or bruising at the injection site. The blood sample is then sent to a laboratory for analysis. Depending on your situation, your doctor may ask you to have the test done at a specific time, such as just before your next dose (trough level) or at a particular time of day.
What do the results mean?
Results are typically reported in micrograms per milliliter (μg/mL) or milligrams per liter (mg/L). The therapeutic reference range for barbital is generally between 1-5 μg/mL, though this may vary slightly between laboratories. Results below the therapeutic range may indicate that the dose is too low or that the patient is not taking the medication as prescribed. Results above the therapeutic range may suggest overdose or toxicity, which can cause symptoms such as severe drowsiness, slurred speech, impaired coordination, slow breathing, or even coma in extreme cases.
Reference range
Therapeutic: 2-10 mg/L; reference range is not established for individuals not receiving barbital therapyN/A
No special preparation required. Specimen should be collected prior to next scheduled dose for therapeutic monitoring.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to fast before this test?
What are the side effects of barbital?
How often do I need this test?
What happens if my level is too high?
Is barbital still commonly prescribed?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy