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Complete Blood Count (CBC): What It Is and Why It Matters

Published: August 9, 2026Updated: August 17, 2026

A screening test to detect the presence of barbiturates (sedative medications) in your blood or body fluid.

Quick summary

{"This test checks if barbiturate medications are present in your body","It helps doctors monitor proper medication levels or detect possible overdose","Results are typically reported as positive or negative","Follow your doctor's instructions about taking medications before the test"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
91028-1
Short code
BARTBS
Synonyms
Barbiturates Fld Ql Scn
Category
chemistry
Sample
serum
Container
Red-top vacuum tube (no anticoagulant) for serum; alternatively, serum separator tube (SST)
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
CPT
80307
SNOMED
395112001
Specimen volume
1-2 mL of serum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
2–24 hours
Order
routine

A complete blood count, or CBC, is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets, to give your care team a clear picture of your overall health.

The barbiturates test is a screening method that detects whether barbiturate drugs are present in your body fluid (such as blood/serum). Barbiturates are a class of sedative-hypnotic medications that were historically used for sedation, sleep disorders, and seizure control. Examples include phenobarbital, pentobarbital, and secobarbital.

A healthcare professional will draw a small sample of blood, usually from a vein in your arm, using a thin needle. The sample is then sent to a laboratory for analysis, and the blood draw itself typically takes only a few minutes.

A healthcare professional will collect a sample of your blood (serum) from a vein in your arm. The sample is then sent to a laboratory where it is tested using screening methods, typically immunoassay techniques, to detect the presence of barbiturates.

Your doctor may order a CBC as part of a routine checkup or to help diagnose conditions such as anemia, infection, inflammation, or blood disorders. It can also be used to monitor an existing condition or to see how well a treatment is working.

Your doctor may order this test for several reasons: (1) to monitor the level of barbiturate medication you are taking for seizure control or other medical conditions, (2) to check for signs of drug overdose or toxicity, (3) to evaluate unexplained symptoms like excessive drowsiness, confusion, or breathing problems, or (4) as part of a drug screening in certain clinical situations.

In most cases, no special preparation is needed for a CBC, and you can eat and drink normally beforehand. If other tests require fasting, your doctor will let you know. Tell your care team about any medications, vitamins, or supplements you take, and mention if you have ever felt faint during blood draws.

Follow your doctor's instructions regarding taking your prescribed barbiturate medications before the test. Do not stop taking prescribed medications unless your doctor tells you to. Inform your doctor about all medications, supplements, and herbal products you are taking, as some substances may affect test results.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: serum

No fasting required. Patient should be informed that barbiturates may be prescribed medications or drugs of abuse. Specimen collection should follow chain-of-custody procedures if used for forensic or medicolegal purposes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is important for therapeutic drug monitoring (TDM) in patients taking barbiturates for epilepsy or other conditions. Proper dosing is critical because the difference between a therapeutic dose and a toxic dose can be small. The test helps ensure drug levels are within the therapeutic range and not reaching toxic levels. A positive result may indicate proper medication adherence, but very high levels may suggest overdose, which can cause serious symptoms like severe drowsiness, respiratory depression, or even coma. In emergency settings, this test helps guide treatment for suspected barbiturate overdose.

Frequently asked questions

Will the test tell me how much medication is in my system?
This is a screening test that typically provides a positive or negative result. If a more precise measurement is needed, your doctor may order a follow-up test called therapeutic drug monitoring that measures the exact level of barbiturates in your blood.
How long do barbiturates stay in my system?
The duration varies depending on the specific barbiturate. Short-acting barbiturates may clear within a few days, while long-acting ones like phenobarbital can remain detectable for several weeks. Your doctor can provide more specific information based on your medication.
Are there any risks from this test?
The risks are minimal and similar to any routine blood draw. You may experience slight pain, bruising, or bleeding at the puncture site. In rare cases, fainting or infection may occur.
What do the results mean?
A negative result means no barbiturates were detected at the time of testing. A positive result indicates the presence of barbiturates. Your doctor will interpret the results in the context of your medical history, current medications, and symptoms to determine if the level is appropriate, too high, or too low.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy