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Barbituratesmecql

Published: August 9, 2026Updated: August 17, 2026

This test checks if a newborn has been exposed to barbiturate medications before birth by testing the baby's first stool (meconium).

Quick summary

{"Detects barbiturate exposure during pregnancy","Meconium can show drug use in the last half of pregnancy","Results help doctors provide appropriate care","Testing is usually part of routine newborn screening when needed","Positive results do not mean a mother intentionally harmed her baby"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
40412-9
Short code
Barbiturates Mec Ql
Synonyms
Barbiturates Mec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

The Barbiturate Meconium Test is a laboratory test that looks for traces of barbiturates in a newborn's meconium (the first dark stool passed by a baby after birth). Barbiturates are a type of sedative medication sometimes used during pregnancy for conditions like seizures, anxiety, or as sleep aids.

How does it work?

When a pregnant person takes barbiturates, the medication can cross the placenta and reach the developing baby. The baby metabolizes the drug, and traces of it can accumulate in the meconium, which forms during the last half of pregnancy. By testing meconium, doctors can detect if the baby was exposed to these medications before birth.

Why is this test done?

This test is typically ordered when healthcare providers suspect a baby may have been exposed to barbiturates during pregnancy. Reasons may include: signs of withdrawal symptoms in the newborn, a known history of barbiturate use by the mother, or as part of a broader toxicology screening when indicated.

What happens during the test?

A small sample of meconium is collected from the baby's diaper and sent to a laboratory for analysis. The test looks for the presence of barbiturates or their metabolites. No special preparation is needed, and the sample collection is simple and harmless to the baby.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings2

Frequently asked questions

Does a positive result mean my baby is in danger?
Not necessarily. While some babies may experience withdrawal symptoms, many do not. Healthcare providers will monitor your baby closely and provide treatment if needed. Early detection allows for better care.
Will this test be reported to authorities?
Testing protocols vary by location. Healthcare providers focus on the baby's health and will discuss any reporting requirements with you. The primary goal is to ensure proper medical care for your newborn.
What if I took barbiturates as prescribed by my doctor?
This is important information to share with your healthcare provider. If you were prescribed barbiturates for a medical condition, your doctor needs to know this to properly care for your baby. Many medications are safe during pregnancy when monitored, and your healthcare team can help manage any effects on your newborn.
How long do barbiturates stay in meconium?
Meconium begins to form around the 12th week of pregnancy and accumulates until birth. Detection in meconium generally indicates exposure during the second and third trimesters, providing a longer detection window compared to urine or blood tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy