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Barbituratessalqlcfm

Published: August 9, 2026Updated: August 16, 2026

A test to detect the presence of barbiturates (sedative medications) in saliva/oral fluid using a confirmatory method.

Quick summary

{"Detects barbiturate drugs in saliva to monitor medication use or exposure","May be used for therapeutic drug monitoring or substance abuse screening","Saliva collection is non-invasive and convenient"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72451-8
Short code
BARB-SAL
Synonyms
Barbiturates Sal Ql Cfm
Category
chemistry
Sample
serum
Container
Sterile saliva collection device or oral fluid collection tube with stabilizing buffer; secure transport container
Units
N/A
Ref low
10
Ref high
50
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
CPT
80307
SNOMED
361110002
Specimen volume
1-2 mL of oral fluid (saliva)
Stability
Room temperature: up to 7 days; Refrigerated (2-8°C): up to 14 days; Frozen (-20°C or below): up to 30 days for forensic specimens
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

这是什么测试?

Barbiturate saliva test is a laboratory test that detects the presence of barbiturates in your saliva (oral fluid). Barbiturates are a class of sedative-hypnotic medications that were historically prescribed for anxiety, insomnia, and seizure disorders. This test uses a confirmatory method, which is a more specific and accurate testing technique to identify barbiturate compounds.

为什么需要这个测试?

Your healthcare provider may order this test for several reasons: to monitor if you are taking barbiturate medications as prescribed (therapeutic drug monitoring), to check for accidental or intentional overdose, or as part of a substance abuse screening program. It may also be used in forensic or employment settings where drug testing is required.

测试如何进行?

A healthcare professional will collect a sample of your saliva using a special collection device. The process is simple and involves placing a collection swab in your mouth to absorb saliva. The sample is then sent to a laboratory for analysis using confirmatory testing methods such as gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass spectrometry (LC-MS/MS), which can accurately identify and quantify specific barbiturate compounds.

我需要做准备吗?

Before the test, inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medicines, and supplements. Some substances may interfere with the test results. Do not eat, drink, smoke, or chew gum for at least 10-30 minutes before the saliva sample is collected, as these activities may affect the sample quality.

Reference range

Negative (cutoff concentration typically 10-50 ng/mL depending on laboratory and specific barbiturate analyte)N/A

Specimen: serum

No special patient preparation required. Patient should rinse mouth with water and avoid eating, drinking, or using oral hygiene products for at least 10 minutes prior to specimen collection to avoid contamination.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How long do barbiturates stay detectable in saliva?
Barbiturates can typically be detected in saliva for 1-5 days after last use, depending on the specific drug, dosage, and individual metabolism. Short-acting barbiturates may be detectable for shorter periods, while long-acting ones like phenobarbital may remain detectable longer.
Will this test show if I took my medication as prescribed?
Yes, this test can confirm whether you have taken barbiturate medication. However, it cannot determine exactly when or how much you took. Therapeutic drug monitoring through blood tests is often used alongside saliva testing for more precise dosage adjustments.
Can second-hand exposure cause a positive result?
It is unlikely that second-hand exposure to barbiturates would cause a positive result in a confirmatory test, as these tests are designed to detect only significant levels of the drug. However, it is important to disclose any potential exposure to your healthcare provider.
What do the results mean?
A positive result indicates that barbiturates were detected in your saliva. A negative result means no barbiturates were detected at the time of testing. Your healthcare provider will interpret the results in the context of your medical history, medications, and the reason for testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy