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Barbituratesspecql

Published: August 9, 2026Updated: August 17, 2026

A blood test that detects the presence of barbiturate drugs in your system.

Quick summary

{"Barbiturates are sedative-hypnotic medications used for anesthesia, seizure control, and sleep disorders","This test checks if barbiturates are present in your blood serum","Results can help monitor drug therapy or investigate suspected overdose","Common barbiturates include phenobarbital, pentobarbital, and secobarbital","The test is performed on a blood sample collected from a vein"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
10363-0
Short code
BARBS
Synonyms
Barbiturates Spec Ql
Category
chemistry
Sample
serum
Container
Red-top serum collection tube (no anticoagulant) or serum separator tube (SST)
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Immunoassay (e.g., enzyme immunoassay, fluorescence polarization immunoassay) with confirmation by Gas Chromatography-Mass Spectrometry (GC-MS) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
80345
SNOMED
395112001
Specimen volume
1-2 mL of serum (minimum 0.5 mL)
Stability
Serum stable for 24 hours at room temperature (15-25°C), 7 days refrigerated at 2-8°C, and up to 30 days frozen at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
25
TAT
4–72 hours
Order
routine

What is this test?

The Barbiturates test is a laboratory test that detects the presence of barbiturate drugs in your blood serum. Barbiturates are a class of medications that act as central nervous system depressants. They are prescribed for various medical conditions including epilepsy, insomnia, and as anesthetic agents during surgery.

This test uses your blood sample to determine whether barbiturate substances are present. The test result is typically reported as either 'Present' or 'Not Detected', indicating whether barbiturates were found in your bloodstream at the time the sample was taken.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: serum

No fasting required. Specimen should be collected prior to administration of next dose for therapeutic monitoring. Inform the laboratory of all medications, including prescription, over-the-counter, and herbal supplements, as barbiturates may cross-react with other substances.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Monitoring therapeutic drug levels: For patients taking prescribed barbiturates (such as phenobarbital for seizures), this test helps ensure the drug level is within the therapeutic range and not reaching toxic levels.

Detecting overdose or toxicity: Barbiturate overdose can cause serious symptoms including respiratory depression, coma, and potentially death. This test helps healthcare providers diagnose and treat overdose situations.

Evaluating unexplained symptoms: If a patient presents with symptoms like excessive drowsiness, confusion, or slow breathing, this test can help determine if barbiturates are the cause.

Compliance monitoring: The test may be used to verify that patients are taking their prescribed medications as directed.

Frequently asked questions

Why do I need this test?
Your healthcare provider may order this test if you are taking barbiturate medications to monitor your drug levels, if you have symptoms of barbiturate overdose, or if you are experiencing unexplained drowsiness or breathing problems.
How is the test performed?
A healthcare professional will draw a small blood sample from a vein in your arm. The sample will be sent to a laboratory where it will be analyzed for the presence of barbiturates.
Do I need to prepare for the test?
Follow your healthcare provider's instructions regarding medication use. Some medications and substances may affect test results. Inform your provider about all medications, supplements, and herbal products you are taking.
What do the results mean?
A 'Present' result means barbiturates were detected in your blood. A 'Not Detected' result means no barbiturates were found. Your healthcare provider will interpret these results in the context of your medical history, symptoms, and medications.
Are there risks to this test?
The risks are minimal and include slight pain or bruising at the injection site, and in rare cases, infection or excessive bleeding.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy