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Complete Blood Count (CBC) Test

Published: August 9, 2026Updated: August 17, 2026

A urine test that checks for the presence of barbiturates, a type of central nervous system depressant medication.

Quick summary

{"This test detects barbiturates (sedative medications) in your urine","It is commonly used for drug screening, medication monitoring, or checking for overdose","Results are reported as positive or negative for the presence of barbiturates","A positive result may indicate legitimate use, misuse, or overdose","Certain substances and medical conditions can affect test results"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
19271-6
Short code
BARBU
Synonyms
Barbiturates Tested Ur Scn
Category
chemistry
Sample
urine
Container
Sterile, leak-proof urine collection container without preservatives
Units
N/A
Ref low
3.5
Ref high
7.2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
CPT
80307
SNOMED
167580008
Specimen volume
30-50 mL random urine specimen
Stability
Refrigerated (2-8°C): up to 7 days; Frozen (-20°C): up to 30 days for confirmation testing; Room temperature: up to 24 hours
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test? A complete blood count, or CBC, is a common blood test that measures the different cells in your blood, including red blood cells, white blood cells, and platelets, and it is often included in a routine checkup.

A urine barbiturate screen is a laboratory test that detects the presence of barbiturates in your urine. Barbiturates are a class of medications that act as central nervous system depressants. They are typically prescribed for sedation, anesthesia, seizure control, or sleep disorders. This screening test uses immunoassay technology to identify whether barbiturates or their metabolites are present in the urine sample.

Why is this test ordered? Doctors order a CBC to evaluate your overall health and to help detect a wide range of conditions, such as anemia, infections, and blood disorders. It may also be used to monitor an existing condition or to see how well a treatment is working.

Healthcare providers may order this test for several reasons: (1) routine drug screening for employment, sports, or legal purposes; (2) monitoring patients on barbiturate therapy to ensure appropriate use; (3) evaluating patients with symptoms of barbiturate overdose or poisoning; (4) checking for substance abuse or dependency; and (5) monitoring during drug addiction treatment programs.

How is the test performed? A health care professional will draw a small sample of blood, usually from a vein in your arm, using a thin needle. The sample is then sent to a laboratory, where it is analyzed, and the entire process typically takes only a few minutes.

You will be asked to provide a urine sample in a clean container. The collection process is similar to a standard urine test. The sample is then sent to a laboratory where it undergoes screening using immunoassay techniques. If the initial screen is positive, confirmatory testing (such as gas chromatography-mass spectrometry) may be performed to identify specific types of barbiturates. The test does not require any special preparation, though you should inform your healthcare provider about all medications you are taking.

What do the results mean? Your results will show whether your red blood cells, white blood cells, and platelets are within the normal range. Abnormal levels can point to conditions such as anemia, infection, inflammation, or clotting problems, and your doctor will interpret them together with your symptoms and medical history.

Results are typically reported as either 'Positive' (barbiturates detected) or 'Negative' (no barbiturates detected). A positive result indicates that barbiturates or their metabolites were found in your urine. This could be due to: legitimate prescription use, misuse or abuse of the medication, or accidental overdose. A negative result means no barbiturates were detected at the screening cutoff level. It's important to note that different barbiturates remain detectable in urine for varying lengths of time, typically ranging from several days to weeks after use, depending on the specific drug and individual factors.

Reference range

NCBI: Uric Acid Male 3.5-7.2 mg/dL; Female 2.5-6.8 mg/dLN/A

Specimen: urine

No special preparation required. Patient should be informed that certain prescription medications containing barbiturates (e.g., phenobarbital, butabarbital) may produce positive results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The urine barbiturate screen is clinically significant for detecting barbiturate exposure, which is important in emergency settings for diagnosing overdose (characterized by symptoms like respiratory depression, confusion, and slurred speech). It helps monitor medication compliance in patients prescribed barbiturates for epilepsy or sleep disorders. In addiction medicine, it aids in identifying substance use disorders and monitoring recovery progress. The test is also valuable in forensic and occupational health settings for drug-free workplace programs. However, interpretation requires clinical correlation, as false positives can occur with certain medications, and false negatives may result from very recent use or very old use.

Frequently asked questions

How long do barbiturates stay in urine?
The detection window varies depending on the specific barbiturate, dosage, frequency of use, and individual metabolism. Short-acting barbiturates like pentobarbital may be detectable for 2-4 days, while long-acting ones like phenobarbital can be detected for 2-3 weeks or longer after last use.
Can other medications cause a false positive result?
Yes, certain medications may cause false positive results on urine barbiturate screens. These may include some antibiotics, NSAIDs, and other substances. Always inform your healthcare provider about all medications, supplements, and herbal products you are taking before the test.
Do I need to fast before this test?
No fasting is required for a urine barbiturate screen. You can eat and drink normally before providing the urine sample. However, you should stay well hydrated to ensure an adequate urine sample.
Will a positive result show up on a pre-employment drug screen?
Yes, if barbiturates are detected in your urine and you have a valid prescription, you should provide documentation to the testing facility. Many workplaces accept legally prescribed medications, but policies vary by employer. Discuss any prescribed barbiturate use with your employer or the testing facility beforehand.
What should I do if my test is positive?
If your test is positive and you have a valid prescription for barbiturates, provide documentation to your healthcare provider or the testing facility. If you do not have a prescription, discuss the result with your healthcare provider, who can evaluate for potential misuse, addiction, or accidental exposure and recommend appropriate treatment or support services.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy