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Understanding Your Laboratory Test: A Patient's Guide to Testing, Procedure, and Results

Published: August 9, 2026Updated: August 10, 2026

The basophil count test measures the number of basophils, a type of white blood cell, in your blood.

Quick summary

{"Basophils are white blood cells that help your body fight infections and respond to allergens","This test is usually part of a complete blood count (CBC) with differential","Abnormal basophil levels may indicate allergies, infections, or certain blood disorders","The test requires a simple blood draw","Results are typically available within a day"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
26444-0
Short code
BASO
Synonyms
Basophils # Bld
Category
chemistry
Sample
whole-blood
Container
EDTA (lavender/purple-top) vacutainer tube; alternatively K2-EDTA or K3-EDTA microtainer for pediatric collections
Units
N/A
Ref low
0.02
Ref high
0.1
Fasting
false
Population
adult
Sex
all
Age range
0–150 years
Method
Automated flow cytometry with fluorescent staining and impedance counting (e.g., Sysmex XN-series, Beckman Coulter DxH)
CPT
85025 (with automated differential) or 85027 (without differential)
SNOMED
41898006 |Basophil count| with LOINC-linked concepts available
Specimen volume
3 mL whole blood (minimum 1 mL for adult; 500 uL for pediatric capillary)
Stability
Stable at room temperature (18-25°C) for 4 hours; refrigerated (2-8°C) for up to 24 hours. Best analyzed within 4 hours of collection for optimal cell preservation.
Hemolysis max
100
Lipemia max
200
TAT
1–4 hours
Order
routine

This is a laboratory test that helps your doctor evaluate your health by measuring specific substances in a sample of your blood, urine, or other body fluid. The results provide important information about how well your organs are functioning and whether there are signs of infection, disease, or other medical conditions that may need further attention or treatment.

The basophil count test measures the number of basophils in your blood. Basophils are a type of white blood cell (WBC) that play an important role in your immune system. They are part of your body's defense against parasites and are involved in allergic reactions.

Your doctor may order this test to help diagnose a medical condition, monitor an ongoing illness, check how well a treatment is working, or screen for health problems before symptoms appear. It can also be part of a routine checkup to establish baseline values and detect changes in your health over time, allowing earlier intervention when needed.

Your healthcare provider may order a basophil count as part of a routine complete blood count (CBC) test, or to help diagnose conditions such as allergies, infections, autoimmune disorders, or blood cancers like leukemia. It may also be used to monitor your response to certain treatments.

The test is usually performed in a laboratory, hospital, or your doctor's office. A trained healthcare professional will collect a small sample, most often by drawing blood from a vein in your arm with a thin needle. The procedure takes only a few minutes, and you may feel a brief pinch. Afterward, a bandage is placed on the site, and the sample is sent to the laboratory for analysis.

A healthcare professional will draw a small sample of blood from a vein in your arm. The blood sample is then sent to a laboratory for analysis. You do not need to fast or prepare in any special way for this test.

Your results are compared with reference ranges that show the expected levels for healthy individuals. Values within the normal range generally suggest no problems were detected, while values that are too high or too low may point to an infection, inflammation, organ dysfunction, or another condition. Abnormal results do not always mean you are sick, so your doctor will review them together with your symptoms, medical history, and other tests before recommending next steps.

Normal basophil counts are typically low. High basophil levels (basophilia) may indicate allergic reactions, infections, inflammatory conditions, certain cancers, or bone marrow disorders. Low basophil levels (basopenia) are less common and may occur during pregnancy, with hyperthyroidism, or with certain infections.

Reference range

Adults: 0.02-0.10 x10^3/uL (20-100 cells/uL); 0.5-1.0% of total WBCN/A

Specimen: whole-blood

No special patient preparation required. Fasting not required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Basophil counts help healthcare providers assess immune function and diagnose various conditions. Elevated levels may suggest allergic reactions (such as hay fever, asthma, or drug allergies), chronic inflammation, infections (like chickenpox or tuberculosis), or blood disorders (including chronic myeloid leukemia). Low levels are less common but may be seen in certain infections, hyperthyroidism, or during acute allergic reactions when basophils are recruited into tissues.

Frequently asked questions

Do I need to fast before the basophil count test?
No, you do not need to fast before this test. You can eat and drink normally before having your blood drawn.
Is the basophil count test dangerous?
The test is very safe. The risks are minimal and include slight bruising, bleeding, or infection at the needle site. These complications are rare and usually mild.
What can cause high basophil levels?
High basophil levels can be caused by allergies, asthma, parasitic infections, inflammatory conditions (such as rheumatoid arthritis), certain medications, and blood cancers like leukemia. Your healthcare provider will interpret your results in context of your overall health and other test results.
Can basophil levels change quickly?
Yes, basophil counts can change based on various factors including time of day, stress levels, infections, and medications. This is why your healthcare provider may order multiple tests over time to track changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy